Crotamiton

Base Information

Chemical Name:Crotamiton
CAS No.:124236-29-9
Molecular Formula:C13H17NO
Molecular Weight:203.284
Hs Code.:
European Community (EC) Number:207-596-3,806-597-1
NSC Number:758951,78382
UNII:2EEH27851Y
DSSTox Substance ID:DTXSID101256463
Nikkaji Number:J28.784I,J2.055I
Wikipedia:Crotamiton
Wikidata:Q2439845
NCI Thesaurus Code:C65353
RXCUI:21766
Metabolomics Workbench ID:42660
ChEMBL ID:CHEMBL1200709
Mol file:124236-29-9.mol

Synonyms:crotamiton;Eurax

Suppliers and Price of Crotamiton

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
trans-Crotamiton
1g
$ 50.00

TCI Chemical
N-Ethyl-o-crotonotoluidide >95.0%(GC)
25g
$ 318.00

TCI Chemical
N-Ethyl-o-crotonotoluidide >95.0%(GC)
5g
$ 103.00

Medical Isotopes, Inc.
trans-Crotamiton
10 g
$ 1460.00

Crysdot
(E)-N-Ethyl-N-(o-tolyl)but-2-enamide 95+%
100g
$ 619.00

Biosynth Carbosynth
trans-Crotamiton
20 g
$ 80.00

Biosynth Carbosynth
trans-Crotamiton
10 g
$ 50.00

Alfa Aesar
trans-Crotamiton 97%
5g
$ 31.90

Alfa Aesar
trans-Crotamiton 97%
1g
$ 15.80

Total 11 raw suppliers

Chemical Property of Crotamiton

Chemical Property:

Refractive Index:1.5400-1.5440
Boiling Point:155°C/13mmHg(lit.)
PSA：20.31000
Density:0.987
LogP:2.92400
Water Solubility.:Soluble in water (1:500), alcohol, methanol, ether, and ethanol.
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:203.131014166
Heavy Atom Count:15
Complexity:235

Purity/Quality:

97% ^*data from raw suppliers

trans-Crotamiton ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(C1=CC=CC=C1C)C(=O)C=CC
Isomeric SMILES:CCN(C1=CC=CC=C1C)C(=O)/C=C/C
Uses Crotamiton is an anti-parasitic agent. Crotamiton is used both as a scabicidal (for treating scabies) and as a general antipruritic. Crotamiton was used to study the photocatalytic decomposition of crotamiton in aqueous solution using TiO2. N-Ethyl-o-crotonotoluidide (Crotamiton) was used to treat scabies and various pruritic dermatoses.

Technology Process of Crotamiton

There total 7 articles about Crotamiton which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.6%

: 625-35-4,3488-22-0,10487-71-5
trans-chrotonyl chloride

: 94-68-8
N-ethyl-2-methylaniline

: 124236-29-9
crotamiton

Guidance literature:: With sodium hydroxide; In water; Petroleum ether; at 10 - 70 ℃; for 6.5h; Concentration;

Reference yield:

: 15307-86-5
[2-(2,6-dichloroanilino)phenyl]acetic acid

: 124236-29-9
crotamiton

Guidance literature:

Reference yield:

: 107-93-7
(E)-but-2-enoic acid

: 94-68-8
N-ethyl-2-methylaniline

: 124236-29-9
crotamiton

Guidance literature:: (E)-but-2-enoic acid; With sodium methylate; In methanol; ethylbenzene; at 50 ℃;

N-ethyl-2-methylaniline; With phosphorus trichloride; In ethylbenzene; at 60 - 110 ℃; for 2.5h; Temperature;