Technology Process of 3-(4-(1H-pyrrol-1-yl)phenyl)-N-ethyl-N-(o-tolyl)butanamide
There total 3 articles about 3-(4-(1H-pyrrol-1-yl)phenyl)-N-ethyl-N-(o-tolyl)butanamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; caesium carbonate; XPhos;
In
cyclopentyl methyl ether; water;
at 95 ℃;
Inert atmosphere;
DOI:10.1021/ja108949w
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium hydrogenfluoride / water; acetonitrile / 2 h
2: palladium diacetate; caesium carbonate; XPhos / cyclopentyl methyl ether; water / 95 °C / Inert atmosphere
With
potassium hydrogenfluoride; palladium diacetate; caesium carbonate; XPhos;
In
cyclopentyl methyl ether; water; acetonitrile;
2: Suzuki-Miyaura cross-coupling;
DOI:10.1021/ja108949w
- Guidance literature:
-
Multi-step reaction with 3 steps
1: methanol; bis[2-(diphenylphosphino)phenyl] ether; copper(l) chloride; sodium t-butanolate / tetrahydrofuran / 20 °C / Inert atmosphere
2: potassium hydrogenfluoride / water; acetonitrile / 2 h
3: palladium diacetate; caesium carbonate; XPhos / cyclopentyl methyl ether; water / 95 °C / Inert atmosphere
With
methanol; potassium hydrogenfluoride; palladium diacetate; caesium carbonate; bis[2-(diphenylphosphino)phenyl] ether; copper(l) chloride; sodium t-butanolate; XPhos;
In
tetrahydrofuran; cyclopentyl methyl ether; water; acetonitrile;
3: Suzuki-Miyaura cross-coupling;
DOI:10.1021/ja108949w