4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde

Base Information

Chemical Name:4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde
CAS No.:173282-22-9
Molecular Formula:C13H7F2NO4
Molecular Weight:279.2
Hs Code.:
DSSTox Substance ID:DTXSID40363166
Wikidata:Q82146750
Mol file:173282-22-9.mol

Synonyms:173282-22-9;4-(2,4-difluorophenoxy)-3-nitrobenzenecarbaldehyde;4-(2,4-difluorophenoxy)-3-nitrobenzaldehyde;C13H7F2NO4;Oprea1_076113;SCHEMBL13220974;DTXSID40363166;YGA28222;MFCD00794806;AKOS005070546;5L-501S;CS-0318440;W15167;J-513262;4-(2,4-difluorophenoxy)-3-nitrobenzenecarbaldehyde, AldrichCPR

Suppliers and Price of 4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde
100mg
$ 60.00

Matrix Scientific
4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde >95%
5g
$ 524.00

Matrix Scientific
4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde >95%
1g
$ 228.00

Matrix Scientific
4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde >95%
500mg
$ 181.00

Crysdot
4-(2,4-Difluorophenoxy)-3-nitrobenzaldehyde 95+%
5g
$ 325.00

AK Scientific
4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde
1g
$ 357.00

Total 4 raw suppliers

Chemical Property of 4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde

Chemical Property:

Melting Point:88-90°
Boiling Point:341.5±42.0 °C(Predicted)
PSA：72.12000
Density:1.454±0.06 g/cm3(Predicted)
LogP:4.00100
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:279.03431403
Heavy Atom Count:20
Complexity:363

Purity/Quality:

98%min ^*data from raw suppliers

4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C=O)[N+](=O)[O-])OC2=C(C=C(C=C2)F)F

Technology Process of 4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde

There total 1 articles about 4-(2,4-Difluorophenoxy)-3-nitrobenzenecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 367-27-1
2,4-difluorophenol

: 16588-34-4
4-chloro-3-nitro-benzaldehyde

: 173282-22-9
4-(2,4-difluorophenoxy)-3-nitrobenzaldehyde

Guidance literature:: With potassium hydroxide; at 120 ℃; for 2h;
DOI:10.1055/s-1995-4129

Reference yield: 83.0%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 173282-22-9
4-(2,4-difluorophenoxy)-3-nitrobenzaldehyde

: 4-(2,4-difluorophenoxy)-3-nitrocinnamate

Guidance literature:: With sodium hydride; In 1,2-dimethoxyethane; at 60 ℃; for 1h;
DOI:10.1055/s-1995-4129

Reference yield:

: 173282-22-9
4-(2,4-difluorophenoxy)-3-nitrobenzaldehyde

: 173282-26-3
4-(2,4-difluorophenoxy)-3-methanesulfonamidophenylpropionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / NaH / 1,2-dimethoxy-ethane / 1 h / 60 °C

2: 100 percent / H₂ / 10percent Pd/C / ethyl acetate / 2 h / 2550.2 Torr / Ambient temperature

3: 89 percent / pyridine / CH₂Cl₂ / 1 h / Ambient temperature

4: 86 percent / NaOH / ethanol; H₂O / 2 h / Heating

With pyridine; sodium hydroxide; hydrogen; sodium hydride; palladium on activated charcoal; In 1,2-dimethoxyethane; ethanol; dichloromethane; water; ethyl acetate;
DOI:10.1055/s-1995-4129