4-ETHOXY-3,5-DIMETHYLBENZALDEHYDE

Base Information

• Chemical Name: 4-ETHOXY-3,5-DIMETHYLBENZALDEHYDE
• CAS No.: 861376-63-8
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.231
• Hs Code.: 2912499000
• Mol file: 861376-63-8.mol

Synonyms:4-ETHOXY-3,5-DIMETHYLBENZALDEHYDE

Chemical Property of 4-ETHOXY-3,5-DIMETHYLBENZALDEHYDE

Chemical Property:

• PSA: 26.30000
• LogP: 2.51460

Purity/Quality:

98%min ^*data from raw suppliers

4-Ethoxy-3,5-dimethylbenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ETHOXY-3,5-DIMETHYLBENZALDEHYDE

There total 4 articles about 4-ETHOXY-3,5-DIMETHYLBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-hydroxy-3,5-dimethylbenzaldehyde (2233-18-3) + ethyl iodide (75-03-6) → 4-ethoxy-3,5-dimethylbenzaldehyde (861376-63-8)

Guidance literature:

With potassium carbonate; In ethanol; for 4h; Inert atmosphere; Reflux;

DOI:10.1007/s11172-017-1850-4

Reference yield:

2.6-dimethylphenol (576-26-1,25134-01-4) → 4-ethoxy-3,5-dimethylbenzaldehyde (861376-63-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / water / 4 h / Reflux; Inert atmosphere

2: potassium carbonate / ethanol / 4 h / Inert atmosphere; Reflux

With potassium carbonate; acetic acid; In ethanol; water;

DOI:10.1007/s11172-017-1850-4

Reference yield:

2,6-dimethyl-1-ethoxylbenzene (26620-08-6) → 4-ethoxy-3,5-dimethylbenzaldehyde (861376-63-8)

Guidance literature:

upstream raw materials:

2,6-dimethyl-1-ethoxylbenzene

2.6-dimethylphenol

4-hydroxy-3,5-dimethylbenzaldehyde

ethyl iodide

Refernces

• 1、 -. "INHIBITORS OF SERINE PROTEASES FOR THE TREATMENT OF HCV INFECTIONS". Page/Page column 477. . Retrieved 2008/12/07.