Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate

Base Information

Chemical Name:Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate
CAS No.:343864-83-5
Molecular Formula:C₆H₈N₂O₃
Molecular Weight:156.141
Hs Code.:
DSSTox Substance ID:DTXSID70515297
Mol file:343864-83-5.mol

Synonyms:343864-83-5;Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate;DTXSID70515297

Suppliers and Price of Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate

Chemical Property:

PSA：71.25000
LogP:-1.00720
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:156.05349212
Heavy Atom Count:11
Complexity:234

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(=NNC1=O)C(=O)OC

Technology Process of Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate

There total 3 articles about Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 759-65-9
diethyl oxalpropionate

: 343864-83-5
4-Methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / hydrazine hydrate / ethanol / 0.5 h / Heating

2: 15percent aq. HCl / 15 h / Heating

3: HCl (gas) / 15 h / Heating

With hydrogenchloride; hydrazine hydrate; In ethanol;
DOI:10.1021/jo00341a007

Reference yield:

: 60178-92-9
4-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester

: 343864-83-5
4-Methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 15percent aq. HCl / 15 h / Heating

2: HCl (gas) / 15 h / Heating

With hydrogenchloride;
DOI:10.1021/jo00341a007