3,6-Diphenyl-1,4,2,5-dioxadiazine

Base Information

• Chemical Name: 3,6-Diphenyl-1,4,2,5-dioxadiazine
• CAS No.: 20434-86-0
• Molecular Formula: C14H10N2O2
• Molecular Weight: 238.24
• Mol file: 20434-86-0.mol

Synonyms:3,6-Diphenyl-1,4,2,5-dioxadiazine

Chemical Property of 3,6-Diphenyl-1,4,2,5-dioxadiazine

Chemical Property:

• PSA: 43.18000
• LogP: 1.62800

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,6-Diphenyl-1,4,2,5-dioxadiazine

There total 12 articles about 3,6-Diphenyl-1,4,2,5-dioxadiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (59938-06-6) + benzohydroximoyl chloride (698-16-8) → 3-phenyl-5-(3-phenylisoxazol-4-yl)-5-(trifluoromethyl)-[1,4,2]dioxazole (931386-53-7) + 3,6-diphenyl-[1,4,2,5]dioxadiazine (20434-86-0)

Guidance literature:

With sodium hydrogencarbonate; In benzene; at 20 ℃; for 48h;

DOI:10.1016/j.tet.2006.12.059

Reference yield: 52.0%

methyl (E)-4,4-dimethoxy-3-(pyrrolidin-1-yl)but-2-enoate (116273-92-8) + benzohydroximoyl chloride (698-16-8) → methyl 5-dimethoxymethyl-3-phenylisoxazole-4-carboxylate (161126-42-7) + 3,6-diphenyl-[1,4,2,5]dioxadiazine (20434-86-0)

Guidance literature:

With triethylamine; In dichloromethane; for 3h; Ambient temperature;

Reference yield: 40.0%

phenylhydroxamoyl chloride (934-16-7) → 3,6-diphenyl-[1,4,2,5]dioxadiazine (20434-86-0)

Guidance literature:

With pyridine; triethylamine; In ethanol; for 20h;

DOI:10.1039/b716915a

upstream raw materials:

benzonitrile oxide

pyridine

benzohydroximoyl chloride

α-picoline