3-Chloro-2,4-difluoro-6-nitroaniline

Base Information

Chemical Name:3-Chloro-2,4-difluoro-6-nitroaniline
CAS No.:50408-94-1
Molecular Formula:C6H3ClF2N2O2
Molecular Weight:208.552
Hs Code.:2921420090
DSSTox Substance ID:DTXSID90443063
Wikidata:Q82260759
Mol file:50408-94-1.mol

Synonyms:3-Chloro-2,4-difluoro-6-nitroaniline;50408-94-1;Benzenamine, 3-chloro-2,4-difluoro-6-nitro-;SCHEMBL7784764;DTXSID90443063;LXZZOYWXUAYAKR-UHFFFAOYSA-N;MFCD11035858;AKOS016011167;AM62528;SB78545;AS-30468;CS-0211451

Suppliers and Price of 3-Chloro-2,4-difluoro-6-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-chloro-2,4-difluoro-6-nitroaniline
500mg
$ 220.00

TRC
3-chloro-2,4-difluoro-6-nitroaniline
100mg
$ 65.00

Matrix Scientific
3-Chloro-2,4-difluoro-6-nitroaniline 95+%
250mg
$ 416.00

Matrix Scientific
3-Chloro-2,4-difluoro-6-nitroaniline 95+%
1g
$ 924.00

Crysdot
3-Chloro-2,4-difluoro-6-nitroaniline 95+%
10g
$ 452.00

Crysdot
3-Chloro-2,4-difluoro-6-nitroaniline 95+%
100g
$ 2565.00

Crysdot
3-Chloro-2,4-difluoro-6-nitroaniline 95+%
25g
$ 941.00

American Custom Chemicals Corporation
3-CHLORO-2,4-DIFLUORO-6-NITROANILINE 95.00%
1G
$ 326.55

AK Scientific
3-Chloro-2,4-difluoro-6-nitroaniline
1g
$ 477.00

Total 16 raw suppliers

Chemical Property of 3-Chloro-2,4-difluoro-6-nitroaniline

Chemical Property:

Melting Point:96-97 °C
Boiling Point:317.1±37.0 °C(Predicted)
PKA:-2.85±0.25(Predicted)
PSA：71.84000
Density:1.682±0.06 g/cm3(Predicted)
LogP:3.21300
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:207.9851114
Heavy Atom Count:13
Complexity:213

Purity/Quality:

99.00% ^*data from raw suppliers

3-chloro-2,4-difluoro-6-nitroaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(C(=C1F)Cl)F)N)[N+](=O)[O-]

Technology Process of 3-Chloro-2,4-difluoro-6-nitroaniline

There total 3 articles about 3-Chloro-2,4-difluoro-6-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 170098-83-6
3-chloro-2,4-difluoro-1-(trifluoroacetamido)-6-nitrobenzene

: 50408-94-1
3-chloro-2,4-difluoro-6-nitroaniline

Guidance literature:: With potassium carbonate; In methanol; for 4h; Ambient temperature;
DOI:10.1021/jm00022a003

Reference yield:

: 2613-34-5
2,4-difluoro-3-chloro-aniline

: 50408-94-1
3-chloro-2,4-difluoro-6-nitroaniline

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / dioxane / 20 h / Ambient temperature

2: 95 percent / concd. H₂SO₄, concd. HNO₃ / 4 h / 0 °C

3: 87 percent / 7percent aq. K₂CO₃ / methanol / 4 h / Ambient temperature

With sulfuric acid; nitric acid; potassium carbonate; In 1,4-dioxane; methanol;
DOI:10.1021/jm00022a003

Reference yield:

: 170098-82-5
3-Chloro-2,4-difluoro-(trifluoroacetamido)benzene

: 50408-94-1
3-chloro-2,4-difluoro-6-nitroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / concd. H₂SO₄, concd. HNO₃ / 4 h / 0 °C

2: 87 percent / 7percent aq. K₂CO₃ / methanol / 4 h / Ambient temperature

With sulfuric acid; nitric acid; potassium carbonate; In methanol;
DOI:10.1021/jm00022a003