4-Chloro-3,5-difluorobenzene-1,2-diamine

Base Information

Chemical Name:4-Chloro-3,5-difluorobenzene-1,2-diamine
CAS No.:170098-84-7
Molecular Formula:C6H5ClF2N2
Molecular Weight:178.569
Hs Code.:2921511990
European Community (EC) Number:640-890-3
DSSTox Substance ID:DTXSID80443673
Wikidata:Q82261575
Mol file:170098-84-7.mol

Synonyms:4-Chloro-3,5-difluorobenzene-1,2-diamine;170098-84-7;4-Chloro-1,2-diamino-3,5-difluorobenzene, 4-Chloro-3,5-difluorophenylene-1,2-diamine;4-chloro-3,5-difluoro-1,2-phenylenediamine;SCHEMBL7779798;DTXSID80443673;IHUBEIMJZSCCER-UHFFFAOYSA-N

Suppliers and Price of 4-Chloro-3,5-difluorobenzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Chloro-3,5-difluorobenzene-1,2-diamine

Chemical Property:

PSA：52.04000
LogP:2.94500
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:178.0109322
Heavy Atom Count:11
Complexity:147

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(C(=C1F)Cl)F)N)N

Technology Process of 4-Chloro-3,5-difluorobenzene-1,2-diamine

There total 4 articles about 4-Chloro-3,5-difluorobenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 50408-94-1
3-chloro-2,4-difluoro-6-nitroaniline

: 170098-84-7
1,2-diamino-4-chloro-3,5-difluorobenzene

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 3h; under 1034.3 - 1551.4 Torr;
DOI:10.1021/jm00022a003

Reference yield:

: 2613-34-5
2,4-difluoro-3-chloro-aniline

: 170098-84-7
1,2-diamino-4-chloro-3,5-difluorobenzene

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / dioxane / 20 h / Ambient temperature

2: 95 percent / concd. H₂SO₄, concd. HNO₃ / 4 h / 0 °C

3: 87 percent / 7percent aq. K₂CO₃ / methanol / 4 h / Ambient temperature

4: 96 percent / H₂ / 10percent Pd/C / methanol / 3 h / 1034.3 - 1551.4 Torr

With sulfuric acid; hydrogen; nitric acid; potassium carbonate; palladium on activated charcoal; In 1,4-dioxane; methanol;
DOI:10.1021/jm00022a003

Reference yield:

: 170098-83-6
3-chloro-2,4-difluoro-1-(trifluoroacetamido)-6-nitrobenzene

: 170098-84-7
1,2-diamino-4-chloro-3,5-difluorobenzene

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / 7percent aq. K₂CO₃ / methanol / 4 h / Ambient temperature

2: 96 percent / H₂ / 10percent Pd/C / methanol / 3 h / 1034.3 - 1551.4 Torr

With hydrogen; potassium carbonate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00022a003