(-)-3-OXO-6-BETA-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-ALPHA-BENZOYLOXY-2-OXABICYCLO[3.3.0!OCTAN, 99+%

Base Information

Chemical Name:(-)-3-OXO-6-BETA-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-ALPHA-BENZOYLOXY-2-OXABICYCLO[3.3.0!OCTAN, 99+%
CAS No.:64982-34-9
Molecular Formula:C₂₁H₃₀O₅Si
Molecular Weight:390.552
Hs Code.:

Synonyms:(-)-3-OXO-6-BETA-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-ALPHA-BENZOYLOXY-2-OXABICYCLO[3.3.0!OCTAN, 99+%;(-)-3-OXO-6-B-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-A-BENZOYLOXY-2-OXABICYCLO[3.3.0]OCTAN;(-)-3-Oxo-6-beta-t.-butyldimethylsilyloxymethyl-7-alpha-benzoyloxy-2-oxabicyclo[3.3.0]octa;[3aR-(3aalpha,4alpha,5beta,6aalpha)]-5-(Benzoyloxy)-4-[[[(tert-butyl)dimethylsilyl]oxy]methyl]hexahydro-2H-cyclopenta[b]furan-2-one

Suppliers and Price of (-)-3-OXO-6-BETA-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-ALPHA-BENZOYLOXY-2-OXABICYCLO[3.3.0!OCTAN, 99+%

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of (-)-3-OXO-6-BETA-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-ALPHA-BENZOYLOXY-2-OXABICYCLO[3.3.0!OCTAN, 99+%

Chemical Property:

Refractive Index:1.5120 (estimate)
Boiling Point:248.88°C (rough estimate)
PSA：61.83000
Density:1.12
LogP:4.18540

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (-)-3-OXO-6-BETA-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-ALPHA-BENZOYLOXY-2-OXABICYCLO[3.3.0!OCTAN, 99+%

There total 1 articles about (-)-3-OXO-6-BETA-T.-BUTYLDIMETHYLSILYLOXYMETHYL-7-ALPHA-BENZOYLOXY-2-OXABICYCLO[3.3.0!OCTAN, 99+% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39746-00-4,53275-42-6,53275-53-9,81244-64-6,93133-00-7,172821-93-1
Benzoic acid (3aR,5R,6aS)-4-hydroxymethyl-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester

: 18162-48-6
tert-butyldimethylsilyl chloride

: 64982-34-9,81203-77-2
Benzoic acid (3aR,5R,6aS)-4-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide;

Reference yield:

: 64982-34-9,81203-77-2
Benzoic acid (3aR,5R,6aS)-4-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester

: 81266-62-8
Benzoic acid (2R,3aR,6aS)-1-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-octahydro-pentalen-2-yl ester

Guidance literature:: Multi-step reaction with 7 steps

1: tetrahydrofuran / -70 °C

2: TsOH / toluene / 25 °C

3: K₂CO₃ / methanol / 25 °C

4: Collins-reagent / or Jones-reagent

5: 1.) 1,5-diazabicyclo<4.3.0>non-5-ene, 2.) NaBH₄ / 1.) 0 deg C, THF, 2.) CH₃OH

6: 1,4-diazabicyclo<2.2.2>octane / toluene; H₂O / 110 °C

7: 0.17 h / 0 °C

With 1,4-diaza-bicyclo[2.2.2]octane; sodium tetrahydroborate; Collins oxidation agent; DBN; potassium carbonate; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; water; toluene;

Reference yield:

: 64982-34-9,81203-77-2
Benzoic acid (3aR,5R,6aS)-4-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester

: 81266-59-3
Benzoic acid (3aR,5R,6aS)-4-(tert-butyl-dimethyl-silanyloxymethyl)-2-[1-ethoxycarbonyl-meth-(E)-ylidene]-hexahydro-cyclopenta[b]furan-5-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / -70 °C

2: TsOH / toluene / 25 °C

With toluene-4-sulfonic acid; In tetrahydrofuran; toluene;