Ethyl 2-(3-bromophenyl)-2,2-difluoroacetate

Base Information

Chemical Name:Ethyl 2-(3-bromophenyl)-2,2-difluoroacetate
CAS No.:885068-75-7
Molecular Formula:C10H9BrF2O2
Molecular Weight:279.081
Hs Code.:
European Community (EC) Number:848-275-3

Synonyms:ETHYL 2-(3-BROMOPHENYL)-2,2-DIFLUOROACETATE;885068-75-7;Ethyl (3-bromophenyl)(difluoro)acetate;MFCD16036663;ethyl alpha,alpha-difluoro-3-bromophenylacetate;SCHEMBL1657919;Ethyl(3-bromophenyl)difluoroacetate;Ethyl (3-bromophenyl)difluoroacetate;AKOS024259041;CS-12159;SY038880;EN300-746860;(3-bromo-phenyl)-difluoro-acetic acid ethyl ester;A922609;ETHYL2-(3-BROMOPHENYL)-2,2-DIFLUOROACETATE;Benzeneacetic acid, 3-bromo-a,a-difluoro-, ethyl ester

Suppliers and Price of Ethyl 2-(3-bromophenyl)-2,2-difluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Ethyl 2-(3-bromophenyl)-2,2-difluoroacetate

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:277.97540
Heavy Atom Count:15
Complexity:234

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C1=CC(=CC=C1)Br)(F)F

Technology Process of Ethyl 2-(3-bromophenyl)-2,2-difluoroacetate

There total 4 articles about Ethyl 2-(3-bromophenyl)-2,2-difluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 885068-75-7
2-(3-bromophenyl)-2,2-difluoroacetic acid ethyl ester

Guidance literature:: With copper; In dimethyl sulfoxide; at 30 - 50 ℃; for 16h; Inert atmosphere;

Reference yield:

: 591-18-4
1-Bromo-3-iodobenzene

: 667-27-6
Ethyl bromodifluoroacetate

: 885068-75-7
2-(3-bromophenyl)-2,2-difluoroacetic acid ethyl ester

Guidance literature:: With zinc/copper couple; In dimethyl sulfoxide; at 55 ℃; for 60h;

Reference yield:

: 14062-30-7
ethyl 2-(3-bromophenyl)acetate

: 885068-75-7
2-(3-bromophenyl)-2,2-difluoroacetic acid ethyl ester

Guidance literature:: ethyl 2-(3-bromophenyl)acetate; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.333333h;

With N-fluorobis(benzenesulfon)imide; In tetrahydrofuran; at -78 ℃; for 3.5h;