Methyl 7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate

Base Information

Chemical Name:Methyl 7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate
CAS No.:65844-56-6
Molecular Formula:C₁₃H₁₆O₃
Molecular Weight:220.268
Hs Code.:2918990090
DSSTox Substance ID:DTXSID20516678
Nikkaji Number:J2.454.920H
Mol file:65844-56-6.mol

Synonyms:Methyl 7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate;65844-56-6;methyl 7-methoxy-1,2,3,4-tetrahydro-2-naphthoate;SCHEMBL545767;DTXSID20516678;LGHVETGTLVYZEO-UHFFFAOYSA-N;FT-0758229;methyl 7-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylate;methyl 7-methoxy-1,2,3,4tetrahydronaphthalene-2-carboxylate;Methyl7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate

Suppliers and Price of Methyl 7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate 95+%
1g
$ 377.00

Chemenu
methyl7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate 95%
1g
$ 356.00

American Custom Chemicals Corporation
METHYL-7-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE 95.00%
5MG
$ 502.11

Total 6 raw suppliers

Chemical Property of Methyl 7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate

Chemical Property:

PSA：35.53000
LogP:1.97310
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.109944368
Heavy Atom Count:16
Complexity:252

Purity/Quality:

99% ^*data from raw suppliers

Methyl7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(CCC(C2)C(=O)OC)C=C1

Technology Process of Methyl 7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate

There total 9 articles about Methyl 7-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 120072-87-9
methyl 1,2,3,4-tetrahydro-7-methoxy-1-oxo-2-naphthalenecarboxylate

: 65844-56-6
methyl 1,2,3,4-tetrahydro-7-methoxy-2-naphthalenecarboxylate

Guidance literature:: With sulfuric acid; palladium 10% on activated carbon; hydrogen; acetic acid; for 2.5h; under 1551.49 Torr;
DOI:10.1021/jm101479y

Reference yield:

: 935740-88-8
4-methoxy-2-[(trimethylsilyl)methyl]benzyl alcohol

: 65844-56-6
methyl 1,2,3,4-tetrahydro-7-methoxy-2-naphthalenecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 412 mg / pyridine / 4-(dimethylamino)pyridine / CH₂Cl₂ / 0 - 20 °C

2: DPPE-Pd(η³-C3H5)Cp / dimethylsulfoxide / 72 h / 120 °C

With pyridine; dmap; In dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ja070012l

Reference yield:

: 52289-55-1
(4-methoxy-2-methylphenyl)methanol

: 65844-56-6
methyl 1,2,3,4-tetrahydro-7-methoxy-2-naphthalenecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: BuLi; N,N,N'N'-tetramethylethylenediamine / diethyl ether; hexane / 24 h / Heating

1.2: diethyl ether; hexane / 3 h / 20 °C

1.3: aq. H₂SO₄ / diethyl ether; hexane / 20 h

2.1: 412 mg / pyridine / 4-(dimethylamino)pyridine / CH₂Cl₂ / 0 - 20 °C

3.1: DPPE-Pd(η³-C3H5)Cp / dimethylsulfoxide / 72 h / 120 °C

With pyridine; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; dmap; In diethyl ether; hexane; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ja070012l