3-Benzoylphenylboronic acid pinacol ester

Base Information

• Chemical Name: 3-Benzoylphenylboronic acid pinacol ester
• CAS No.: 949022-45-1
• Molecular Formula: C19H21BO3
• Molecular Weight: 308.185
• Hs Code.: 2931900090
• Mol file: 949022-45-1.mol

Synonyms:AMTB058;A-9207;3-BENZOYLPHENYLBORONIC ACID PINACOL ESTER;phenyl[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanone;

Chemical Property of 3-Benzoylphenylboronic acid pinacol ester

Chemical Property:

• PSA: 35.53000
• LogP: 3.21680

Purity/Quality:

98%Min ^*data from raw suppliers

3-Benzoylphenylboronicacidpinacolester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Benzoylphenylboronic acid pinacol ester

There total 3 articles about 3-Benzoylphenylboronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3-chlorobenzophenone (1016-78-0) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → benzophenone (119-61-9) + phenyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone (949022-45-1)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; triethylamine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; 2,2'-bis(di-tert-butylphosphino)diphenyl ether; In 1,4-dioxane; at 100 ℃; for 48h;

DOI:10.3987/COM-09-S(S)63

Reference yield: 51.0%

phenyl 3-benzoylbenzoate + bis(pinacol)diborane (73183-34-3) → phenyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone (949022-45-1)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; tributylphosphine; lithium carbonate; In 1,4-dioxane; at 160 ℃; for 36h; chemoselective reaction; Glovebox; Sealed tube;

DOI:10.1002/chem.201604504

Reference yield:

→ phenyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone (949022-45-1)

Guidance literature:

upstream raw materials:

3-chlorobenzophenone

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

bis(pinacol)diborane

Refernces

• 1、 Murata, Miki,Sambommatsu, Tomoko,Oda, Takeshi,Watanabe, Shinji,Masuda, Yuzuru. "Palladium- or nickel-catalyzed coupling reaction of dialkoxyboranes with chloroarenes: arylation of 1,3,2-dioxaborolanes or l,3,2-dioxaborinanes". experimental part. p. 213 - 218. Retrieved 2010/05/03.