3-(tert-ButyldiMethylsilyl)Morphinone

Base Information

Chemical Name:3-(tert-ButyldiMethylsilyl)Morphinone
CAS No.:91265-75-7
Molecular Formula:C23H31NO3Si
Molecular Weight:397.59
Hs Code.:
Mol file:91265-75-7.mol

Synonyms:(5α)-7,8-Didehydro-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-4,5-epoxy-17-Methyl-Morphinan-6-one

Suppliers and Price of 3-(tert-ButyldiMethylsilyl)Morphinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
3-(tert-Butyldimethylsilyl)morphinone
100 mg
$ 1052.00

Biosynth Carbosynth
3-(tert-Butyldimethylsilyl)morphinone
50 mg
$ 578.50

Biosynth Carbosynth
3-(tert-Butyldimethylsilyl)morphinone
25 mg
$ 318.00

Biosynth Carbosynth
3-(tert-Butyldimethylsilyl)morphinone
10 mg
$ 174.90

Biosynth Carbosynth
3-(tert-Butyldimethylsilyl)morphinone
250 mg
$ 1912.50

AK Scientific
(4S,4Ar,7aR,12bS)-9-[tert-butyl(dimethyl)silyl]oxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
100mg
$ 1470.00

Total 1 raw suppliers

Chemical Property of 3-(tert-ButyldiMethylsilyl)Morphinone

Chemical Property:

PSA：38.77000
LogP:4.02260

Purity/Quality:

95% ^*data from raw suppliers

3-(tert-Butyldimethylsilyl)morphinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Protected Morphinone (M652350), a toxic metabolite of Morphine.

Technology Process of 3-(tert-ButyldiMethylsilyl)Morphinone

There total 7 articles about 3-(tert-ButyldiMethylsilyl)Morphinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.7%

: 467-02-7
dihydromorphinone

: 18162-48-6
tert-butyldimethylsilyl chloride

: 91265-75-7
3-(_tbutyldimethylsilyl)morphinone

Guidance literature:: With sodium hydride; In tetrahydrofuran;
DOI:10.1248/cpb.34.4439

Reference yield: 91.0%

: 91265-70-2
3-(_tbutyldimethylsilyl)morphine

: 91265-75-7
3-(_tbutyldimethylsilyl)morphinone

Guidance literature:: With manganese(IV) oxide; In chloroform; for 0.333333h; Ambient temperature;
DOI:10.1016/S0040-4020(01)80016-8

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 91265-75-7
3-(_tbutyldimethylsilyl)morphinone

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / tetrahydrofuran / 40 h / 25 °C

2: silver carbonate / benzene / 2 h / Heating

With silver carbonate; In tetrahydrofuran; benzene;
DOI:10.1021/jm00376a026