1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE

Base Information

Chemical Name:1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE
CAS No.:886364-57-4
Molecular Formula:C7H3BrF3NO
Molecular Weight:254.0040296
Hs Code.:
Mol file:886364-57-4.mol

Synonyms:1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE

Suppliers and Price of 1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethanone 95+%
1g
$ 515.00

Chemenu
1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethanone 95%
1g
$ 482.00

American Custom Chemicals Corporation
1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE 95.00%
5MG
$ 497.42

Alichem
1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethanone
1g
$ 436.80

Total 9 raw suppliers

Chemical Property of 1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE

Chemical Property:

Boiling Point:248.9±40.0 °C(Predicted)
PKA:-1.77±0.10(Predicted)
PSA：29.96000
Density:1.730±0.06 g/cm3(Predicted)
LogP:2.58910
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE

There total 3 articles about 1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.81%

: 626-05-1
2,6-Dibromopyridine

: 360-95-2
2,2,2-Trifluoro-1-morpholin-4-yl-ethanone

: 886364-57-4
1-(6-bromopyridin-2-yl)-2,2,2-trifluoroethan-1-one

Guidance literature:: 2,6-Dibromopyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

2,2,2-Trifluoro-1-morpholin-4-yl-ethanone; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;

Reference yield:

: 626-05-1
2,6-Dibromopyridine

: 383-63-1
ethyl trifluoroacetate,

: 886364-57-4
1-(6-bromopyridin-2-yl)-2,2,2-trifluoroethan-1-one

: 1-(6-bromopyridin-2-yl)-2,2,2-trifluoroethane-1,1-diol

Guidance literature:: 2,6-Dibromopyridine; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1h;

ethyl trifluoroacetate,; In diethyl ether; hexane; at -78 ℃; for 2h; Overall yield = 82 percent; Overall yield = 6.68 g;
DOI:10.1039/d1cc04556c

Reference yield:

: 626-05-1
2,6-Dibromopyridine

: 431-47-0
trifluoroacetic acid-methyl ester

: 886364-57-4
1-(6-bromopyridin-2-yl)-2,2,2-trifluoroethan-1-one

Guidance literature:: 2,6-Dibromopyridine; With n-butyllithium; In tetrahydrofuran; diethyl ether; hexane; at -95 - -90 ℃; Inert atmosphere;

trifluoroacetic acid-methyl ester; In tetrahydrofuran; diethyl ether; hexane; at -100 - -90 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/om901045s