(5,6)-Epoxy-17a-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal)

Base Information

Chemical Name:(5,6)-Epoxy-17a-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal)
CAS No.:117898-52-9
Molecular Formula:C25H38O6
Molecular Weight:434.56562
Hs Code.:
Mol file:117898-52-9.mol

Synonyms:(5,6)-Epoxy-17a-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal);(5β,6β)-Epoxy-17α-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal)

Suppliers and Price of (5,6)-Epoxy-17a-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(5-BETA,6-BETA)-EPOXY-17-ALPHA-HYDROXY-PREGNANE-3,20-DIONE-3,20-BIS(ETHYLENEKETAL) 95.00%
5MG
$ 499.72

Total 2 raw suppliers

Chemical Property of (5,6)-Epoxy-17a-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal)

Chemical Property:

PSA：69.68000
LogP:3.39760

Purity/Quality:

97% ^*data from raw suppliers

(5-BETA,6-BETA)-EPOXY-17-ALPHA-HYDROXY-PREGNANE-3,20-DIONE-3,20-BIS(ETHYLENEKETAL) 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An intermediate for the synthesis of Progestogens.

Technology Process of (5,6)-Epoxy-17a-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal)

There total 6 articles about (5,6)-Epoxy-17a-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3386-00-3
17-hydroxy-5-pregnene-3,20-dione 3,20-bisethylene ketal

: 3496-78-4,117898-52-9
C₂₅H₃₈O₆

Guidance literature:: With 2,2,2-trifluoroacetamide; dihydrogen peroxide; sodium carbonate; In toluene; at 80 ℃; Solvent; Reagent/catalyst; Temperature;

Reference yield:

: 3386-00-3
17-hydroxy-5-pregnene-3,20-dione 3,20-bisethylene ketal

: 3496-78-4
3,3;20,20-bis-ethanediyldioxy-5,6α-epoxy-5α-pregnan-17-ol

: 117898-52-9
3,3;20,20-bis-ethanediyldioxy-5,6β-epoxy-5β-pregnan-17-ol

Guidance literature:: With peracetic acid;
DOI:10.1021/ja01544a079

Reference yield:

: 68-96-2
17-hydroxyprogesterone

: 3496-78-4,117898-52-9
C₂₅H₃₈O₆

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid; trimethyl orthoformate / 20 °C / Inert atmosphere

2: sodium carbonate; 2,2,2-trifluoroacetamide; dihydrogen peroxide / toluene / 80 °C

With 2,2,2-trifluoroacetamide; dihydrogen peroxide; sodium carbonate; toluene-4-sulfonic acid; trimethyl orthoformate; In toluene;