Nicotinic Acid-13C1

Base Information

• Chemical Name: Nicotinic Acid-13C1
• CAS No.: 57987-14-1
• Molecular Formula: C6H5NO2
• Molecular Weight: 124.1184
• Mol file: 57987-14-1.mol

Synonyms:Nicotinic Acid-13C1

Chemical Property of Nicotinic Acid-13C1

Chemical Property:

• PSA: 50.19000
• LogP: 0.77980

Purity/Quality:

97%; ≥99% atom 13C ^*data from raw suppliers

Nicotinic Acid-13C1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Isotope labelled analogue of Nicotinic Acid (N429250), also known as vitamin B3, is an essential nutrient that must be obtained from a dietary source in order for normal body function. The administration of Nicotinic Acid in animal models of ischemia was shown to significantly reduce the size of infarction and improve functional recovery. Current findings suggest that nicotinic acid may have therapeutic potential for the treatment of traumatic brain injury.

Technology Process of Nicotinic Acid-13C1

There total 2 articles about Nicotinic Acid-13C1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-iodopyridine (1120-90-7) + [13C]Carbon monoxide (1641-69-6) → [carbonyl-13C]nicotinic acid (57987-14-1)

Guidance literature:

With trimethylphenylammonium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 180 ℃; for 0.333333h; under 262526 Torr;

DOI:10.1039/b206420k

Reference yield:

→ [carbonyl-13C]nicotinic acid (57987-14-1)

Guidance literature:

3-Lithiumpyridin, Bu¹³CO3;

DOI:10.1021/ja00859a014

upstream raw materials:

3-iodopyridine

[13C]Carbon monoxide