Amino-PEG8-alcohol

Base Information

Chemical Name:Amino-PEG8-alcohol
CAS No.:352439-37-3
Molecular Formula:C16H35NO8
Molecular Weight:369.451
Hs Code.:2918999090
Mol file:352439-37-3.mol

Synonyms:Amino-PEG8-alcohol;352439-37-3;NH2-PEG8-OH;23-AMINO-3,6,9,12,15,18,21-HEPTAOXATRICOSAN-1-OL;H2N-PEG8-OH;Amino-PEG8-OH;Amino-dPEG(R)8-OH;SCHEMBL39999;DGWYLEGXXDZPEY-UHFFFAOYSA-N;MFCD11041128;AKOS030213462;GS-9365;SB67143;2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol;BP-21502;HY-130200;CS-0105698;C70392

Suppliers and Price of Amino-PEG8-alcohol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-AminooctaethyleneGlycol
100mg
$ 475.00

purepeg
H2N-PEG8-OH min.97%
500 mg
$ 275.00

Iris Biotech GmbH
H2N-dPEG(8)-OH
1 g
$ 580.50

dPEG
Amino-dPEG???-OH
100 mg
$ 250.00

dPEG
Amino-dPEG???-OH
100 mg
$ 200.00

DC Chemicals
Amino-PEG8-alcohol
003
$ 1700.00

BroadPharm
Amino-PEG8-alcohol 98%
1 G
$ 450.00

BroadPharm
Amino-PEG8-alcohol 98%
100 MG
$ 115.00

Biosynth Carbosynth
1-Aminooctaethylene glycol
50 mg
$ 100.00

Biosynth Carbosynth
1-Aminooctaethylene glycol
25 mg
$ 60.00

Total 18 raw suppliers

Chemical Property of Amino-PEG8-alcohol

Chemical Property:

Boiling Point:464.4±40.0 °C(Predicted)
PKA:14.36±0.10(Predicted)
PSA：110.86000
Density:1.091±0.06 g/cm3(Predicted)
LogP:-0.24610
Storage Temp.:-20°C
Solubility.:Soluble in Water, DMSO, DCM, DMF
XLogP3:-2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:22
Exact Mass:369.23626707
Heavy Atom Count:25
Complexity:236

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-AminooctaethyleneGlycol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(COCCOCCOCCOCCOCCOCCOCCO)N
Description Amino-PEG8-alcohol consist of an amino (NH2) and a hydroxyl group (OH). The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The OH group enables further derivatization or replacement with other reactive functional groups.
Uses 1-Aminooctaethylene Glycol is a polyethyleneglycol (PEG) derivative used in the preparation and stabilization of biosensors.

Technology Process of Amino-PEG8-alcohol

There total 13 articles about Amino-PEG8-alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 352439-36-2
α-(2-azidoethyl)-ω-hydroxyhexa(oxyethylene)

: 352439-37-3
23-amino-3 ,6,9,12,15,18,21-heptaoxatricosan-1-ol

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 10h; Inert atmosphere;

Reference yield: 78.0%

: 352439-37-3
23-amino-3 ,6,9,12,15,18,21-heptaoxatricosan-1-ol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol;

Reference yield:

: 112-60-7
Tetraethylene glycol

: 352439-37-3
23-amino-3 ,6,9,12,15,18,21-heptaoxatricosan-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1.1: pyridine

2.1: NaH / dimethylformamide / 0.5 h / 20 °C

2.2: dimethylformamide / 22 h / 20 °C

3.1: 0.51 g / p-TsOH / methanol

4.1: Ph₃P / tetrahydrofuran / 20 h / 20 °C

4.2: 90 percent / H₂O / tetrahydrofuran

With pyridine; sodium hydride; toluene-4-sulfonic acid; triphenylphosphine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; 2.1: Williamson's ether synthesis / 4.1: Staudinger reduction reaction;
DOI:10.1021/jo0012290