N-Benzyloxycarbonylvalylprolinal

Base Information

Chemical Name:N-Benzyloxycarbonylvalylprolinal
CAS No.:91650-00-9
Molecular Formula:C18H24N2O4
Molecular Weight:332.3942
Hs Code.:
DSSTox Substance ID:DTXSID30919611
Mol file:91650-00-9.mol

Synonyms:N-BCVP;N-benzyloxycarbonyl-valylprolinal;N-benzyloxycarbonylvalylprolinal;Z-Val-Prolinal

Suppliers and Price of N-Benzyloxycarbonylvalylprolinal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-Benzyloxycarbonylvalylprolinal

Chemical Property:

Vapor Pressure:2.85E-11mmHg at 25°C
Boiling Point:528.9°Cat760mmHg
Flash Point:273.6°C
PSA：79.20000
Density:1.213g/cm³
LogP:2.26960
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:332.17360725
Heavy Atom Count:24
Complexity:446

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)N1CCCC1C=O)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(C)[C@@H](C(=O)N1CCCC1C=O)NC(=O)OCC2=CC=CC=C2

Technology Process of N-Benzyloxycarbonylvalylprolinal

There total 10 articles about N-Benzyloxycarbonylvalylprolinal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 108807-63-2
Z-L-Val-L-prolinal semicarbazone

: 91650-00-9
Cbz-L-Val-L-propinal

Guidance literature:: With hydrogenchloride; formaldehyd; In ethanol; for 5h; Ambient temperature;
DOI:10.1248/cpb.34.2931

Reference yield:

: 56439-35-1
Cbz-L-Val-L-propinol

: 91650-00-9
Cbz-L-Val-L-propinal

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 ℃;
DOI:10.1016/j.bmc.2003.08.030

Reference yield:

: 71461-30-8
(S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester

: 91650-00-9
Cbz-L-Val-L-propinal

Guidance literature:: Multi-step reaction with 5 steps

1: sodium acetate / aq. ethanol / 0.12 h / 80 °C

2: H₂ / 10 percent palladium-carbon / methanol / 1 h

3: methanol

4: 32 percent / triethylamine / dimethylformamide / 24 h / Ambient temperature

5: 43 percent / 0.12 M HCl, 37 percent formaldehyde / ethanol / 5 h / Ambient temperature

With hydrogenchloride; formaldehyd; hydrogen; sodium acetate; triethylamine; palladium on activated charcoal; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.2931