2-Methoxycarbonylindole-5-boronicacid

Base Information

• Chemical Name: 2-Methoxycarbonylindole-5-boronicacid
• CAS No.: 284660-86-2
• Molecular Formula: C₁₀H₁₀BNO₄
• Molecular Weight: 219.005
• Mol file: 284660-86-2.mol

Synonyms:2-Methoxycarbonylindole-5-boronicacid;[2-(Methoxycarbonyl)-1H-indol-5-yl]boronic acid

Chemical Property of 2-Methoxycarbonylindole-5-boronicacid

Chemical Property:

• Vapor Pressure: 3.46E-10mmHg at 25°C
• Boiling Point: 484.2°C at 760 mmHg
• PKA: 8.55±0.30(Predicted)
• Flash Point: 246.6°C
• PSA: 82.55000
• Density: 1.39g/cm³
• LogP: -0.36570
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-Methoxycarbonylindole-5-boronic acid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methoxycarbonylindole-5-boronicacid

There total 2 articles about 2-Methoxycarbonylindole-5-boronicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

C16H20BNO4 (284660-89-5) + 2,2'-iminobis[ethanol] (111-42-2) → methyl 5-boronyl-indole-2-carboxylate (284660-86-2)

Guidance literature:

C₁₆H₂₀BNO₄; 2,2'-iminobis[ethanol]; In ethyl acetate; at 20 ℃;

With hydrogenchloride; water;

Reference yield:

C14H17BN2O4 → methyl 5-boronyl-indole-2-carboxylate (284660-86-2)

Guidance literature:

With hydrogenchloride; water;

upstream raw materials:

C₁₆H₂₀BNO₄

2,2'-iminobis[ethanol]

Refernces

• 1、 -. "Kinase inhibitors". Page/Page column 29. . Retrieved 2010/11/08.