N-ForMyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]Methyl]dodecyl Ester

Base Information

Chemical Name:N-ForMyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]Methyl]dodecyl Ester
CAS No.:1072902-75-0
Molecular Formula:C₂₉H₅₃NO₅
Molecular Weight:495.744
Hs Code.:
Mol file:1072902-75-0.mol

Synonyms:L-Isoleucine Orlistat;N-ForMyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]Methyl]dodecyl Ester;Orlistat USP Related Compound E

Suppliers and Price of N-ForMyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]Methyl]dodecyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
L-IsoleucineOrlistat
1mg
$ 235.00

Medical Isotopes, Inc.
L-IsoleucineOrlistat
10 mg
$ 2800.00

Total 9 raw suppliers

Chemical Property of N-ForMyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]Methyl]dodecyl Ester

Chemical Property:

PSA：85.19000
LogP:7.72220

Purity/Quality:

> 95% ^*data from raw suppliers

L-IsoleucineOrlistat ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses L-Isoleucine Orlistat is an impurity of Orlistat (O686500). Also, L-Isoleucine Orlistat is a Tetrahydrolipstatin (THL) analogue as inhibitor of the formation or hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). L-Isoleucine Orlistat is an impurity of Orlistat (O686500). Also, L-Isoleucine Orlistat is a Tetrahydrolipstatin (THL) analogue as inhibitor of the formation or hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG).

Technology Process of N-ForMyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]Methyl]dodecyl Ester

There total 7 articles about N-ForMyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]Methyl]dodecyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 1072902-95-4
L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester

: 2258-42-6
formyl acetic anhydride

: 1072902-75-0
OMDM-188

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 0.25h;
DOI:10.1021/jm800978m

Reference yield: 7.2%

: 1558-67-4
formic anhydride

: C₂₈H₅₃NO₄

: 1072902-75-0
OMDM-188

Guidance literature:: In dichloromethane; at -10 - -5 ℃; for 2h;

Reference yield:

: 1072902-88-5
N-[(phenylmethoxy)carbonyl]-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester

: 1072902-75-0
OMDM-188

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / tetrahydrofuran

2: dichloromethane

With palladium on activated charcoal; hydrogen; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2012.05.101