3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)propanal

Base Information

Chemical Name:3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)propanal
CAS No.:264144-78-7
Molecular Formula:C₁₅H₂₁BO₃
Molecular Weight:260.141
Hs Code.:
DSSTox Substance ID:DTXSID10476151
Nikkaji Number:J1.581.165J

Synonyms:264144-78-7;3-PHENYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PROPANAL;SCHEMBL6237791;DTXSID10476151;FT-0757164;A818433

Suppliers and Price of 3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)propanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)propanal

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:260.1583747
Heavy Atom Count:19
Complexity:305

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C(CC=O)C2=CC=CC=C2

Technology Process of 3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)propanal

There total 14 articles about 3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)propanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 104-55-2
3-phenyl-propenal

: 73183-34-3
bis(pinacol)diborane

: 264144-78-7
3-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanal

Guidance literature:: With 2-((1,3-bis(N-butylimidazol-2-ylidene)phenylene)(dimethylamido)bis(iodo))rhodium(III); 2-((1,3-bis(N-butylimidazol-2-ylidene)phenylene)(dimethylamido)bis(chloro))rhodium(III); In methanol; at 22 ℃; for 1h; Solvent; Catalytic behavior; Sealed tube;
DOI:10.1016/j.jorganchem.2015.11.010

Reference yield: 21.0%

: 4,8-dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,6,2-dioxazaborocane

: 104-55-2
3-phenyl-propenal

: 264144-78-7
3-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanal

Guidance literature:: 4,8-dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,6,2-dioxazaborocane; With copper(l) chloride; In dichloromethane; for 0.0833333h; Inert atmosphere;

3-phenyl-propenal; With 2,2,2-trifluoroethanol; In dichloromethane; at 40 ℃; for 3h; regioselective reaction; Inert atmosphere;
DOI:10.1021/jo2003488

Reference yield:

: 14371-10-9
(E)-3-phenylpropenal

: 73183-34-3
bis(pinacol)diborane

: 264144-78-7
3-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanal

Guidance literature:: With sodium t-butanolate; [CuCl((C₆H₅)2C₃H₂N₂(C₆H₂(CH₃)3)2)]; In methanol; β-boration; 87% conversion; 99% chemoselectivity; 40% ee (of S enantiomer);
DOI:10.1021/om800946k