N-(2-bromophenyl)pyridine-4-carboxamide

Base Information

Chemical Name:N-(2-bromophenyl)pyridine-4-carboxamide
CAS No.:252930-61-3
Molecular Formula:C12H9BrN2O
Molecular Weight:277.12
Hs Code.:
DSSTox Substance ID:DTXSID60358231
Nikkaji Number:J1.250.356C
Wikidata:Q82138659
Mol file:252930-61-3.mol

Synonyms:252930-61-3;N-(2-bromophenyl)pyridine-4-carboxamide;N-(2-BROMOPHENYL)-4-PYRIDINECARBOXAMIDE;N-(2-Bromophenyl)isonicotinamide;DTXSID60358231;STK063408;AKOS000173693;FT-0629111;SR-01000234310;SR-01000234310-1

Suppliers and Price of N-(2-bromophenyl)pyridine-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(2-bromophenyl)pyridine-4-carboxamide

Chemical Property:

Vapor Pressure:0.000649mmHg at 25°C
Boiling Point:309.2°C at 760 mmHg
PKA:10.92±0.70(Predicted)
Flash Point:140.8°C
PSA：41.99000
Density:1.559g/cm³
LogP:3.16940
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:275.98983
Heavy Atom Count:16
Complexity:241

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NC(=O)C2=CC=NC=C2)Br

Technology Process of N-(2-bromophenyl)pyridine-4-carboxamide

There total 2 articles about N-(2-bromophenyl)pyridine-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14254-57-0
4-(chlorocarbonyl)pyridine

: 615-36-1
2-bromoaniline

: 252930-61-3
N-(2-bromophenyl)-4-pyridinecarboxamide

Guidance literature:: With pyridine; at 0 - 20 ℃;
DOI:10.1021/jo9909498

Reference yield:

: 55-22-1
pyridine-4-carboxylic acid

: 252930-61-3
N-(2-bromophenyl)-4-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 2 h / Heating

2: Py / 0 - 20 °C

With pyridine; thionyl chloride; 1: Substitution / 2: Acylation;
DOI:10.1021/jo9909498

Reference yield: 96.0%

: 252930-61-3
N-(2-bromophenyl)-4-pyridinecarboxamide

: 2295-47-8
2-(pyridin-4-yl)benzoxazole

Guidance literature:: With copper(l) iodide; 4-phenyl-1-(3-O-benzyl-6-deoxy-1,2-O-isopropylidene-α-D-glucofuranos-6-yl)-1H-1,2,3-triazole; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 10h; Inert atmosphere; Sealed tube;
DOI:10.1021/acscombsci.9b00004