exo-Granisetron (Granisetron Impurity F)

Base Information

Chemical Name:exo-Granisetron (Granisetron Impurity F)
CAS No.:1364914-39-5
Molecular Formula:C₁₈H₂₄N₄O
Molecular Weight:312.415
Hs Code.:
Mol file:1364914-39-5.mol

Synonyms:exo-Granisetron (Granisetron Impurity F);exo-N-(9-Methyl-9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide;Granisetron Impurity F;1-Methyl-N-(9-Methyl-9-aza-bicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxaMide

Suppliers and Price of exo-Granisetron (Granisetron Impurity F)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
exo-Granisetron
10mg
$ 175.00

Total 6 raw suppliers

Chemical Property of exo-Granisetron (Granisetron Impurity F)

Chemical Property:

Melting Point:113-115°C
Boiling Point:532.0±40.0 °C(Predicted)
PKA:12.34±0.20(Predicted)
Density:1.33±0.1 g/cm3(Predicted)
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

exo-Granisetron ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Granisetron Impurity F. Granisetron EP Impurity F. Granisetron Impurity F

Technology Process of exo-Granisetron (Granisetron Impurity F)

There total 16 articles about exo-Granisetron (Granisetron Impurity F) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 107007-95-4
endo-N-(9-methyl-9-azabicyclo<3.3.1>nonan-3-yl)-1H-indazole-3-carboxamide

: 74-88-4
methyl iodide

: 109889-09-0,124998-65-8,121061-98-1,1364914-39-5
granisetron

Guidance literature:: With sodium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield: 89.0%

: 107007-95-4
endo-N-(9-methyl-9-azabicyclo<3.3.1>nonan-3-yl)-1H-indazole-3-carboxamide

: 616-38-6
carbonic acid dimethyl ester

: 109889-09-0,124998-65-8,121061-98-1,1364914-39-5
granisetron

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; Reflux;
DOI:10.1021/acschemneuro.6b00192

Reference yield: 81.0%

: 50890-83-0
1-methyl-1H-indazole-3-carboxylic acid

: 76272-41-8,141650-55-7,76272-56-5
endo-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine

: 109889-09-0,124998-65-8,121061-98-1,1364914-39-5
granisetron

Guidance literature:: With 4-(2-(1,3-dioxa-3a1,8,10-triaza-2,3a,14b-triboradibenzo[fg,op]tetracen-2-yl)phenyl)benzo[c]pyrimido[4,5-e][1,2]azaborinin-6(5H)-ol; In toluene; at 85 ℃; for 16h; Molecular sieve;
DOI:10.1002/chem.201900715