2,4,5-TRIMETHOXYBENZOIC ANHYDRIDE

Base Information

• Chemical Name: 2,4,5-TRIMETHOXYBENZOIC ANHYDRIDE
• CAS No.: 83813-97-2
• Molecular Formula: C20H22O9
• Molecular Weight: 406.389
• Hs Code.: 2918990090
• Mol file: 83813-97-2.mol

Synonyms:2,4,5-TRIMETHOXYBENZOIC ANHYDRIDE

Chemical Property of 2,4,5-TRIMETHOXYBENZOIC ANHYDRIDE

Chemical Property:

• PSA: 98.75000
• LogP: 2.73540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4,5-TRIMETHOXYBENZOIC ANHYDRIDE

There total 2 articles about 2,4,5-TRIMETHOXYBENZOIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

asaronic acid (490-64-2) → 2,4,5-trimethoxybenzoic anhydride (83813-97-2)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In tetrahydrofuran; at 0 ℃;

DOI:10.1021/jm040770b

Reference yield:

2,4,5-trimethoxybenzoyl chloride (42833-66-9) → 2,4,5-trimethoxybenzoic anhydride (83813-97-2)

Guidance literature:

With pyridine;

Reference yield: 48.0%

2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone (55317-02-7) + 2,4,5-trimethoxybenzoic anhydride (83813-97-2) → 5,7-dihydroxy-3-methoxy-2-(2,4,5-trimethoxy-phenyl)-chromen-4-one (852247-39-3)

Guidance literature:

2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone; 2,4,5-trimethoxybenzoic anhydride; With triethylamine; for 0.0833333h; Heating;

With potassium hydroxide; In methanol; for 0.333333h; sonication;

DOI:10.1021/jm040770b

upstream raw materials:

2,4,5-trimethoxybenzoyl chloride

asaronic acid

Downstream raw materials:

5,7-dihydroxy-3-methoxy-2-(2,4,5-trimethoxy-phenyl)-chromen-4-one

3,5,6,7,2',4',5'-heptamethoxyflavone

6-hydroxy-3,5,7,2',4',5'-hexamethoxyflavone

3,4-dimethoxyphenol

Refernces

• 1、 Kocz, Remigiusz,Roestamadji, Juliatiek,Mobashery, Shahriar. "A Convenient Triphosgene-Mediated Synthesis of Symmetric Carboxylic Acid Anhydrides". . p. 2913 - 2914. Retrieved 2007/10/02.