42833-66-9Relevant articles and documents
Synthesis and in silico and in vitro evaluation of trimethoxy-benzamides designed as anti-prion derivatives
Concei??o, Raissa A.,Ascari, Lucas M.,Ferreira, Natália C.,Goes, Carolina F.,Matos, Carolina O.,Pinheiro, Anderson S.,Alves, Marina A.,Souza, Alessandra M. T.,Maia, Rodolfo C.,Caughey, Byron,Cordeiro, Yraima,Barbosa, Maria Letícia C.
, p. 2128 - 2141 (2019)
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are neurodegenerative disorders which affect mammals, including the human species, and arise after the conversion of the monomeric cellular prion protein (PrPC) int
Preparation method of acotiamide hydrochloride impurity
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Paragraph 0020-00021, (2020/08/30)
The invention discloses a preparation method of an acotiamide hydrochloride impurity, which comprises the following steps: carrying out acylating chlorination on raw material 2, 4, 5-trimethoxybenzoicacid to obtain 2, 4, 5-trimethoxybenzoyl chloride, and
Method for synthesizing acotiamide hydrochloride
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Paragraph 0007; 0017; 0018; 0019, (2018/09/08)
The invention discloses a method for synthesizing acotiamide hydrochloride. According to the method, 2,4,5-trimethoxybenzoic acid, thionyl chloride, methylbenzene, dichloromethane, 2-aminothiazole-4-ethyl formate, N-N-dimethyl formamide, pyridine Hydrochl