(1S,2S,3R,5S)-2-Amino-2,6,6-trimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid methyl ester

Base Information

Chemical Name:(1S,2S,3R,5S)-2-Amino-2,6,6-trimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid methyl ester
CAS No.:705949-09-3
Molecular Formula:C12H21NO2
Molecular Weight:211.304
Hs Code.:
DSSTox Substance ID:DTXSID10588708
Wikidata:Q82481563
Mol file:705949-09-3.mol

Synonyms:705949-09-3;(1S,2S,3R,5S)-2-Amino-2,6,6-trimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid methyl ester;DTXSID10588708;Methyl (1S,2S,3R,5S)-2-amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylate

Suppliers and Price of (1S,2S,3R,5S)-2-Amino-2,6,6-trimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(1S,2S,3R,5S)-2-AMINO-2,6,6-TRIMETHYL-BICYCLO(3.1.1)HEPTANE-3-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 501.60

Total 0 raw suppliers

Chemical Property of (1S,2S,3R,5S)-2-Amino-2,6,6-trimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid methyl ester

Chemical Property:

Vapor Pressure:0.0132mmHg at 25°C
Boiling Point:259.1°C at 760 mmHg
Flash Point:121.8°C
PSA：52.32000
Density:1.019g/cm³
LogP:2.25930
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:211.157228913
Heavy Atom Count:15
Complexity:300

Purity/Quality:: (1S,2S,3R,5S)-2-AMINO-2,6,6-TRIMETHYL-BICYCLO(3.1.1)HEPTANE-3-CARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2CC(C(C1C2)(C)N)C(=O)OC)C
Isomeric SMILES:C[C@]1([C@@H](C[C@@H]2C[C@H]1C2(C)C)C(=O)OC)N

Technology Process of (1S,2S,3R,5S)-2-Amino-2,6,6-trimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid methyl ester

There total 2 articles about (1S,2S,3R,5S)-2-Amino-2,6,6-trimethyl-bicyclo[3.1.1]heptane-3-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 67-56-1
methanol

: 35182-62-8,328010-05-5
(1S,2S,5R,7S)-2,8,8-trimethyl-3-azatricyclo[5.1.1.0^2,5]nonan-4-one

: 705949-09-3,705949-02-6
C₁₂H₂₁NO₂

Guidance literature:: With hydrogenchloride; at 80 ℃; for 1.5h; Microwave irradiation;
DOI:10.1055/s-0033-1339291

Reference yield:

: 7785-70-8,25766-18-1
(+)-α-pinene

: 705949-09-3,705949-02-6
C₁₂H₂₁NO₂

Guidance literature:: Multi-step reaction with 2 steps

1: sodium sulfite / 2 h

2: hydrogenchloride / 1.5 h / 80 °C / Microwave irradiation

With hydrogenchloride; sodium sulfite;
DOI:10.1055/s-0033-1339291