(2R,6S)-2,6-bis(iodomethyl)-1,4-dioxane

Base Information

• Chemical Name: (2R,6S)-2,6-bis(iodomethyl)-1,4-dioxane
• CAS No.: 6963-59-3
• Molecular Formula: C₆H₁₀I₂O₂
• Molecular Weight: 367.953
• Mol file: 6963-59-3.mol

Synonyms:1,4-Dioxane, 2,6-bis(iodomethyl)-, cis-;p-Dioxane, 2,6-bis(iodomethyl)-, cis- (8CI);cis-2,6-Bis(iodomethyl)-p-dioxane;NSC 53700;

Chemical Property of (2R,6S)-2,6-bis(iodomethyl)-1,4-dioxane

Chemical Property:

• Vapor Pressure: 0.00014mmHg at 25°C
• Refractive Index: 1.592
• Boiling Point: 343.4°Cat760mmHg
• Flash Point: 161.5°C
• Density: 2.185g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R,6S)-2,6-bis(iodomethyl)-1,4-dioxane

There total 6 articles about (2R,6S)-2,6-bis(iodomethyl)-1,4-dioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Allyl ether (557-40-4) + mercury(II) diacetate (1600-27-7) + nitric acid (7697-37-2,78989-43-2) → cis-2,6-bis-iodomethyl-[1,4]dioxane (6963-59-3) + trans-2,6-Bis(iodomethyl)-1,4-dioxane (56127-59-4)

Guidance literature:

beim Behandeln anschliessend mit wss. Natronlauge und Kaliumjodid und Erwaermen des Reaktionsprodukts mit Jod in wasserhaltigem Chloroform;

DOI:10.1021/ja01558a061

Reference yield:

Allyl ether (557-40-4) → cis-2,6-bis-iodomethyl-[1,4]dioxane (6963-59-3) + (+/-)-trans-2,6-bis-iodomethyl-[1,4]dioxane (6962-99-8,6963-59-3)

Guidance literature:

With mercury(II) diacetate; water; Behandeln mit wss. Kaliumjodid und erwaermen des erhaltenen 2,6-Bis-jodomercuriomethyl-<1,4>dioxans mit Jod in Methanol;

DOI:10.1021/ja01632a028 DOI:10.1021/ja01558a061

Reference yield:

Allyl ether (557-40-4) → cis-2,6-bis-iodomethyl-[1,4]dioxane (6963-59-3) + (+/-)-trans-2,6-bis-iodomethyl-[1,4]dioxane (6962-99-8,6963-59-3)

Guidance literature:

With mercury(II) diacetate; water; Behandeln mit wss. Kaliumjodid und erwaermen des erhaltenen 2,6-Bis-jodomercuriomethyl-<1,4>dioxans mit Jod in Methanol;

DOI:10.1021/ja01632a028 DOI:10.1021/ja01558a061

upstream raw materials:

Allyl ether

mercury(II) diacetate

nitric acid

Downstream raw materials:

2r,6c-bis-hydroxymethyl-[1,4]dioxane