4-Iodobenzenesulfonohydrazide

Base Information

• Chemical Name: 4-Iodobenzenesulfonohydrazide
• CAS No.: 2751-27-1
• Molecular Formula: C6H7IN2O2S
• Molecular Weight: 298.104
• Hs Code.: 2935009090
• European Community (EC) Number: 661-019-3
• DSSTox Substance ID: DTXSID701290198
• Mol file: 2751-27-1.mol

Synonyms:4-iodobenzenesulfonohydrazide;2751-27-1;Benzenesulfonic acid, 4-iodo-, hydrazide;4-IODOBENZENESULFONIC ACID HYDRAZIDE;C6H7IN2O2S;SCHEMBL7817477;DTXSID701290198;CAA75127;MFCD00159283;AKOS009519233;BS-16775;CS-0157411;D82784;A918396

Chemical Property of 4-Iodobenzenesulfonohydrazide

Chemical Property:

• PSA: 80.57000
• LogP: 2.61520
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 297.92730
• Heavy Atom Count: 12
• Complexity: 228

Purity/Quality:

98.5% ^*data from raw suppliers

4-Iodobenzenesulfonohydrazide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1S(=O)(=O)NN)I

Technology Process of 4-Iodobenzenesulfonohydrazide

There total 2 articles about 4-Iodobenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

p-Iodobenzenesulfonyl chloride (98-61-3) → 4-iodobenzenesulfonyl hydrazide (2751-27-1)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 5 ℃; for 0.5h;

DOI:10.1039/c6ra19190h

Reference yield:

→ 4-iodobenzenesulfonyl hydrazide (2751-27-1)

Guidance literature:

aus 4-Jod-benzolsulfochlorid u. Hydrazinhydrat in Bzl.<20grad>;

Reference yield: 95.0%

1-bromo-2,2-diphenylethylene (13249-58-6) + 4-iodobenzenesulfonyl hydrazide (2751-27-1) → (2-((4-iodophenyl)sulfonyl)ethene-1,1-diyl)dibenzene

Guidance literature:

With 1,6-bis(diphenylphosphino)hexane; silver fluoride; In water; at 80 ℃; for 10h; Inert atmosphere; Schlenk technique;

DOI:10.1039/d0cc00784f

upstream raw materials:

p-Iodobenzenesulfonyl chloride

Downstream raw materials:

4-iodo-benzenesulfonic acid-(N'-ξ-D-glucopyranosyl-hydrazide)

D-erythro-Pentulose-<4-jod-benzolsulfonylhydrazon>

3-((4-iodophenyl)thio)-1H-indole

C₁₆H₁₇IOS

Refernces

• 1、 Mulina, Olga M.,Zhironkina, Nataliya V.,Paveliev, Stanislav A.,Demchuk, Dmitry V.,Terent'Ev, Alexander O.. "Electrochemically Induced Synthesis of Sulfonylated N-Unsubstituted Enamines from Vinyl Azides and Sulfonyl Hydrazides". supporting information. p. 1818 - 1824. Retrieved 2020/03/04.
• 2、 Liu, Lixin,Sun, Kang,Su, Lebin,Dong, Jianyu,Cheng, Lei,Zhu, Xiaodong,Au, Chak-Tong,Zhou, Yongbo,Yin, Shuang-Feng. "Palladium-Catalyzed Regio- and Stereoselective Coupling-Addition of Propiolates with Arylsulfonyl Hydrazides: A Pattern for Difunctionalization of Alkynes". supporting information. p. 4023 - 4027. Retrieved 2018/07/15.