2-Azabicyclo[3.1.0]hexane-3-carboxylicacid,ethylester,(1S,3S,5S)-(9CI)

Base Information

Chemical Name:2-Azabicyclo[3.1.0]hexane-3-carboxylicacid,ethylester,(1S,3S,5S)-(9CI)
CAS No.:361440-57-5
Molecular Formula:C8H13NO2
Molecular Weight:155.197
Hs Code.:
Mol file:361440-57-5.mol

Synonyms:2-Azabicyclo[3.1.0]hexane-3-carboxylicacid,ethylester,(1S,3S,5S)-(9CI);1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid ethyl ester;2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, ethyl ester, (1S,3S,5S)-

Suppliers and Price of 2-Azabicyclo[3.1.0]hexane-3-carboxylicacid,ethylester,(1S,3S,5S)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 6 raw suppliers

Chemical Property of 2-Azabicyclo[3.1.0]hexane-3-carboxylicacid,ethylester,(1S,3S,5S)-(9CI)

Chemical Property:

PSA：38.33000
LogP:0.62870

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Azabicyclo[3.1.0]hexane-3-carboxylicacid,ethylester,(1S,3S,5S)-(9CI)

There total 4 articles about 2-Azabicyclo[3.1.0]hexane-3-carboxylicacid,ethylester,(1S,3S,5S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 214193-11-0
(1S,3S,5S)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-formic acid ethyl ester

: 361440-57-5
C₈H₁₃NO₂

Guidance literature:: With hydrogenchloride; water;
DOI:10.1016/j.bmcl.2014.02.055

Reference yield:

: 98-79-3
L-Pyroglutamic acid

: 361440-57-5
C₈H₁₃NO₂

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / 0 - 20 °C

2: dmap; lithium triethylborohydride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid / -50 °C

3: diethylzinc / dichloromethane / -10 °C

4: trifluoroacetic acid / dichloromethane / 0 °C

With dmap; thionyl chloride; diethylzinc; lithium triethylborohydride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1002/anie.201506208

Reference yield:

: 144978-35-8,144978-12-1,251924-83-1
(S)-ethyl N-tert-butoxycarbonylpyroglutamate

: 361440-57-5
C₈H₁₃NO₂

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; lithium triethylborohydride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid / -50 °C

2: diethylzinc / dichloromethane / -10 °C

3: trifluoroacetic acid / dichloromethane / 0 °C

With dmap; diethylzinc; lithium triethylborohydride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1002/anie.201506208