2-(4-Chlorophenyl)-3-hydroxyprop-2-enenitrile

Base Information

Chemical Name:2-(4-Chlorophenyl)-3-hydroxyprop-2-enenitrile
CAS No.:53283-56-0
Molecular Formula:C9H9ClO
Molecular Weight:179.606
Hs Code.:
DSSTox Substance ID:DTXSID00694347
Mol file:53283-56-0.mol

Synonyms:2-(4-chlorophenyl)-3-hydroxyprop-2-enenitrile;53283-56-0;SCHEMBL13740705;DTXSID00694347;QDIJLSOPGGNYKA-UHFFFAOYSA-N;AKOS030242386;2-(4-chloro-phenyl)-3-hydroxy-acrylonitrile

Suppliers and Price of 2-(4-Chlorophenyl)-3-hydroxyprop-2-enenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-3-hydroxyprop-2-enenitrile

Chemical Property:

Vapor Pressure:0.003mmHg at 25°C
Boiling Point:273.334°C at 760 mmHg
Flash Point:149℃
PSA：44.02000
Density:1.177g/cm³
LogP:2.76248
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:179.0137915
Heavy Atom Count:12
Complexity:220

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=CO)C#N)Cl

Technology Process of 2-(4-Chlorophenyl)-3-hydroxyprop-2-enenitrile

There total 2 articles about 2-(4-Chlorophenyl)-3-hydroxyprop-2-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107-31-3
Methyl formate

: 140-53-4
p-chlorobenzyl cyanide

: 53283-56-0
3-hydroxy-2-(p-chlorophenyl)propenenitrile

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2014.08.027

Reference yield:

: 109-94-4
formic acid ethyl ester

: 140-53-4
p-chlorobenzyl cyanide

: 53283-56-0
3-hydroxy-2-(p-chlorophenyl)propenenitrile

Guidance literature:: With sodium methylate; In acetonitrile; at 20 ℃; for 2h; Yield given;

Reference yield:

: 53283-56-0
3-hydroxy-2-(p-chlorophenyl)propenenitrile

: 77-78-1
dimethyl sulfate

: 71870-93-4
2-(4-chlorophenyl)-3-methoxyacrylonitrile

Guidance literature:: 3-hydroxy-2-(p-chlorophenyl)propenenitrile; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

dimethyl sulfate; In tetrahydrofuran; at 40 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2014.08.027