SPhos Pd G2

Base Information

• Chemical Name: SPhos Pd G2
• CAS No.: 1375325-64-6
• Molecular Formula: C₃₈H₄₅ClNO₂PPd
• Molecular Weight: 720.628
• Mol file: 1375325-64-6.mol

Synonyms:Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl) palladiuM(II), Min. 98% [SPhos Palladacycle];Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II);SPhos Pd G2;Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II);2nd Generation SPhos Precatalyst

Chemical Property of SPhos Pd G2

Chemical Property:

• Melting Point: 218°C (dec.)
• PSA: 58.07000
• LogP: 7.31000

Purity/Quality:

97% ^*data from raw suppliers

Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. 98% [SPhos Palladacycle Gen. 2] ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Application in Suzuki-Miyaura coupling:Self-arylation of 1-alkyl-3-bromo-2-phenyl-2,1-borazaronaphthalenes to form 2,1-borazaronaphthols.Suzuki–Miyaura coupling of [Ru(bpy)2]+ with 4-carboxyphenylboronic acid.Suzuki–Miyaura coupling of β-borylated porphyrins with 2-iodoaniline.

Technology Process of SPhos Pd G2

There total 1 articles about SPhos Pd G2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane (657408-07-6) + palladium diacetate (3375-31-3) + 2-phenylaniline (90-41-5) + lithium chloride → chloro(2-dicyclohexylphosphino-2’,6’-dimethoxy-1,1’-biphenyl)[2-(2’-amino-1,1’-biphenyl)]palladium(II) (1375325-64-6)

Guidance literature:

palladium diacetate; 2-phenylaniline; In toluene; at 60 ℃; for 1h;

lithium chloride; In acetone; toluene; at 20 ℃; for 24h;

dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; for 24h;

DOI:10.1039/c5ob02364e

upstream raw materials:

dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane

palladium diacetate

2-phenylaniline