N-[[2-(difluoromethoxy)phenyl]methylidene]hydroxylamine

Base Information

Chemical Name:N-[[2-(difluoromethoxy)phenyl]methylidene]hydroxylamine
CAS No.:332110-52-8
Molecular Formula:C₈H₇F₂NO₂
Molecular Weight:187.146
Hs Code.:
DSSTox Substance ID:DTXSID50366320
Mol file:332110-52-8.mol

Synonyms:N-[[2-(difluoromethoxy)phenyl]methylidene]hydroxylamine;332110-52-8;N-{[2-(difluoromethoxy)phenyl]methylidene}hydroxylamine;Benzaldehyde, 2-(difluoromethoxy)-, oxime (9CI);DTXSID50366320;IUOZSTLMTBFGGX-UHFFFAOYSA-N;AKOS017263343

Suppliers and Price of N-[[2-(difluoromethoxy)phenyl]methylidene]hydroxylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-{[2-(difluoromethoxy)phenyl]methylidene}hydroxylamine
500mg
$ 310.00

TRC
N-{[2-(difluoromethoxy)phenyl]methylidene}hydroxylamine
50mg
$ 45.00

Total 3 raw suppliers

Chemical Property of N-[[2-(difluoromethoxy)phenyl]methylidene]hydroxylamine

Chemical Property:

PSA：41.82000
LogP:2.09610
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:187.04448479
Heavy Atom Count:13
Complexity:176

Purity/Quality:

95% ^*data from raw suppliers

N-{[2-(difluoromethoxy)phenyl]methylidene}hydroxylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C=NO)OC(F)F

Technology Process of N-[[2-(difluoromethoxy)phenyl]methylidene]hydroxylamine

There total 1 articles about N-[[2-(difluoromethoxy)phenyl]methylidene]hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71653-64-0
o-difluoromethoxybenzaldehyde

: 332110-52-8
C₈H₇F₂NO₂

Guidance literature:: With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; at 0 - 20 ℃; for 1h;
DOI:10.1021/acs.jmedchem.7b00907

Reference yield:

: 332110-52-8
C₈H₇F₂NO₂

: C₁₅H₁₃F₂NO₄

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-chloro-succinimide / N,N-dimethyl-formamide / 1 h / 20 - 25 °C

2.1: potassium carbonate / tetrahydrofuran / 0.08 h / -10 °C

2.2: -5 - 35 °C

With N-chloro-succinimide; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b00907

Reference yield:

: 332110-52-8
C₈H₇F₂NO₂

: C₁₄H₁₃F₂NO₃

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-chloro-succinimide / N,N-dimethyl-formamide / 1 h / 20 - 25 °C

2.1: potassium carbonate / tetrahydrofuran / 0.08 h / -10 °C

2.2: -5 - 35 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / -10 °C / Inert atmosphere

With N-chloro-succinimide; lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b00907