Glycine, N-[(2S)-2-(hydroxyMethyl)-1-oxo-3-phenylpropyl]-, ethyl ester

Base Information

Chemical Name:Glycine, N-[(2S)-2-(hydroxyMethyl)-1-oxo-3-phenylpropyl]-, ethyl ester
CAS No.:1314751-83-1
Molecular Formula:C14H19NO4
Molecular Weight:265.309
Hs Code.:
Mol file:1314751-83-1.mol

Synonyms:Glycine, N-[(2S)-2-(hydroxyMethyl)-1-oxo-3-phenylpropyl]-, ethyl ester

Suppliers and Price of Glycine, N-[(2S)-2-(hydroxyMethyl)-1-oxo-3-phenylpropyl]-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Glycine,N-[(2S)-2-(hydroxymethyl)-1-oxo-3-phenylpropyl]-,ethylester
500mg
$ 495.00

Total 5 raw suppliers

Chemical Property of Glycine, N-[(2S)-2-(hydroxyMethyl)-1-oxo-3-phenylpropyl]-, ethyl ester

Chemical Property:

PSA：75.63000
LogP:0.90780

Purity/Quality:

≥95% ^*data from raw suppliers

Glycine,N-[(2S)-2-(hydroxymethyl)-1-oxo-3-phenylpropyl]-,ethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Glycine, N-[(2S)-2-(hydroxyMethyl)-1-oxo-3-phenylpropyl]-, ethyl ester

There total 6 articles about Glycine, N-[(2S)-2-(hydroxyMethyl)-1-oxo-3-phenylpropyl]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 623-33-6
glycine ethyl ester hydrochloride

: 147383-72-0
(S)-2-hydroxymethyl-3-phenylpropionic acid

: 1314751-83-1
ethyl N-[(2S)-2-benzyl-3-hydroxypropanoyl]glycinate

Guidance literature:: glycine ethyl ester hydrochloride; With triethylamine; In dichloromethane; at 10 - 15 ℃; Inert atmosphere;

(S)-2-hydroxymethyl-3-phenylpropionic acid; With dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 32 ℃; for 16h;

Reference yield:

: (S)-1-phenylethylamine (S)-2-benzyl-3-hydroxypropanoate

: 623-33-6
glycine ethyl ester hydrochloride

: 1314751-83-1
ethyl N-[(2S)-2-benzyl-3-hydroxypropanoyl]glycinate

Guidance literature:: (S)-1-phenylethylamine (S)-2-benzyl-3-hydroxypropanoate; With hydrogenchloride; In water; ethyl acetate; at 10 - 30 ℃; for 12h;

glycine ethyl ester hydrochloride; With triethylamine; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 30 ℃; for 13.5h;

Reference yield:

: (R)-3-((S)-2-benzyl-3-hydroxypropanoyl)-4-phenyloxazolidin-2-one

: 1314751-83-1
ethyl N-[(2S)-2-benzyl-3-hydroxypropanoyl]glycinate

Guidance literature:: Multi-step reaction with 3 steps

1.1: dihydrogen peroxide; lithium hydroxide / tetrahydrofuran / 0 - 30 °C

2.1: isopropyl alcohol / 25 - 85 °C

3.1: hydrogenchloride / water; ethyl acetate / 12 h / 10 - 30 °C

3.2: 13.5 h / 0 - 30 °C

With hydrogenchloride; dihydrogen peroxide; lithium hydroxide; In tetrahydrofuran; water; ethyl acetate; isopropyl alcohol;