2-(6,6-DiMethyl-1-cyclohexen-1-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:2-(6,6-DiMethyl-1-cyclohexen-1-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
CAS No.:1142225-97-5
Molecular Formula:C14H25BO2
Molecular Weight:236.162
Hs Code.:
Mol file:1142225-97-5.mol

Synonyms:2-(6,6-DiMethyl-1-cyclohexen-1-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;2-(6,6-dimethylcyclohex-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Suppliers and Price of 2-(6,6-DiMethyl-1-cyclohexen-1-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
500mg
$ 1540.00

AK Scientific
2-(6,6-Dimethyl-1-cyclohexen-1-YL)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1g
$ 1268.00

Total 3 raw suppliers

Chemical Property of 2-(6,6-DiMethyl-1-cyclohexen-1-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane

Chemical Property:

Boiling Point:255.0±33.0 °C(Predicted)
PSA：18.46000
Density:0.94±0.1 g/cm3(Predicted)
LogP:3.75430

Purity/Quality:

97% ^*data from raw suppliers

2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane was used in the preparation of conformationally constrained cyclic carboxylic acid derivatives useful as GPR40 modulators for treating metabolic disorders.

Technology Process of 2-(6,6-DiMethyl-1-cyclohexen-1-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane

There total 2 articles about 2-(6,6-DiMethyl-1-cyclohexen-1-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 32363-23-8
6,6-dimethylcyclohex-1-en-1-yl trifluoromethanesulfonate

: 73183-34-3
bis(pinacol)diborane

: 1142225-97-5
2-(6,6-dimethyl-1-cyclohexen-1-yI)-4,4,5,5-tetramethyI-1,3,2-dioxaborolane

Guidance literature:: With potassium phenolate; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; In toluene; at 50 ℃; for 3.5h; Inert atmosphere;

Reference yield:

: 1193-47-1
2,2-dimethyl-cyclohexanone

: 1142225-97-5
2-(6,6-dimethyl-1-cyclohexen-1-yI)-4,4,5,5-tetramethyI-1,3,2-dioxaborolane

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C

1.2: -78 - 23 °C

2.1: potassium phenolate / bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine / toluene / 3.5 h / 50 °C / Inert atmosphere

With potassium phenolate; lithium diisopropyl amide; bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine; In tetrahydrofuran; toluene;

Reference yield:

: 1142225-97-5
2-(6,6-dimethyl-1-cyclohexen-1-yI)-4,4,5,5-tetramethyI-1,3,2-dioxaborolane

: 1142226-00-3
(2-(6,6-dimethyl-1-cyclohexen-1-yl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 24 h / 23 - 90 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 4.5 h / 0 °C

With lithium aluminium tetrahydride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; N,N-dimethyl-formamide;