8-FLUORO-1-BENZOSUBERONE

Base Information

Chemical Name:8-FLUORO-1-BENZOSUBERONE
CAS No.:24484-21-7
Molecular Formula:C11H11FO
Molecular Weight:178.2
Hs Code.:2914700090
Mol file:24484-21-7.mol

Synonyms:8-FLUORO-1-BENZOSUBERONE;8-Fluoro-1-benzosuberone 96%

Suppliers and Price of 8-FLUORO-1-BENZOSUBERONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
8-Fluoro-1-benzosuberone 96%
5g
$ 801.00

American Custom Chemicals Corporation
8-FLUORO-1-BENZOSUBERONE 95.00%
5G
$ 1166.67

American Custom Chemicals Corporation
8-FLUORO-1-BENZOSUBERONE 95.00%
1G
$ 718.91

AK Scientific
8-Fluoro-1-benzosuberone
5g
$ 618.00

Total 9 raw suppliers

Chemical Property of 8-FLUORO-1-BENZOSUBERONE

Chemical Property:

Vapor Pressure:0.00482mmHg at 25°C
Refractive Index:n20/D 1.541(lit.)
Boiling Point:84-86 °C0.001 mm Hg(lit.)
Flash Point:>230 °F
PSA：17.07000
Density:1.16 g/mL at 25 °C(lit.)
LogP:2.73480

Purity/Quality:

98%,99%, ^*data from raw suppliers

8-Fluoro-1-benzosuberone 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 8-Fluoro-1-benzosuberone was employed in the synthesis of 9-bromo, 2-fluoro substituted, and Z-ring locked (by a trimethylene bridge at C-8 and C-11) crystalline fluorine-substituted derivative of cinnamaldehyde. It was also used in the synthesis of 9-bromo, 2-fluoro substituted, and Z-ring locked (by a trimethylene bridge at C8 and C11) crystalline fluorine substituted bicyclic ring-fused polyene bearing a δ-bromo-α,β,γ,δ-unsaturated ester unit.

Technology Process of 8-FLUORO-1-BENZOSUBERONE

There total 4 articles about 8-FLUORO-1-BENZOSUBERONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24484-22-8
5-(4-fluorophenyl)-pentanoic acid

: 24484-21-7
3-fluoro-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one

Guidance literature:: With polyphosphoric acid; at 90 ℃;
DOI:10.1002/adsc.201800839

Reference yield:

: 462-06-6
fluorobenzene

: 24484-21-7
3-fluoro-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: aluminum (III) chloride / dichloromethane / 5 h / -10 °C

2: palladium 10% on activated carbon; hydrogen; acetic acid / 70 °C

3: polyphosphoric acid / 90 °C

With aluminum (III) chloride; palladium 10% on activated carbon; hydrogen; acetic acid; In dichloromethane;
DOI:10.1002/adsc.201800839

Reference yield:

: 108-55-4
glutaric anhydride,

: 24484-21-7
3-fluoro-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: aluminum (III) chloride / dichloromethane / 5 h / -10 °C

2: palladium 10% on activated carbon; hydrogen; acetic acid / 70 °C

3: polyphosphoric acid / 90 °C

With aluminum (III) chloride; palladium 10% on activated carbon; hydrogen; acetic acid; In dichloromethane;
DOI:10.1002/adsc.201800839