24484-22-8

Basic information

• Product Name: 5-(4-FLUOROPHENYL)VALERIC ACID
• Synonyms: 5-(4'-FLUOROPHENYL)PENTANOIC ACID;5-(4-FLUOROPHENYL)PENTANOIC ACID;5-(4'-FLUOROPHENYL)VALERIC ACID;5-(4-FLUOROPHENYL)VALERIC ACID;5-(4-FLUOROPHENYL)VALERIC ACID 98%;5-(4-Fluorophenyl)valeric acid,97%
• CAS NO: 24484-22-8
• Molecular Formula: C₁₁H₁₃FO₂
• Molecular Weight: 196.22
• Product Categories: C11 to C12;Carbonyl Compounds;Carboxylic Acids
• Mol File: 24484-22-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 75-79 °C(lit.)
• Boiling Point: 335.6 °C at 760 mmHg
• Flash Point: 113 °C
• Appearance: white to light yellow crystalline powder
• Density: 1.15 g/cm³
• PKA: 4.74±0.10(Predicted)
• BRN: 7918899
• CAS DataBase Reference: 5-(4-FLUOROPHENYL)VALERIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-FLUOROPHENYL)VALERIC ACID(24484-22-8)
• EPA Substance Registry System: 5-(4-FLUOROPHENYL)VALERIC ACID(24484-22-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 24484-22-8(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystalline powder

Upstream product

• 591-80-0 pent-4-enoic acid 
• 149437-76-3 5-(4-fluorophenyl)-5-oxopentanoic acid 
• 108-55-4 glutaric anhydride, 
• 462-06-6 fluorobenzene 
• 1357591-15-1 (2E,4E)-ethyl 5-(4'-fluorophenyl)penta-2,4-dienoate 
• 24484-54-6 2-[3-(4-fluorophenyl)propyl]malonic acid 
• 204589-94-6 5-(4-fluorophenyl)-3-pentenoic acid 
• 124-38-9 carbon dioxide 
• 2248-13-7 1-(but-3-en-1-yl)-4-fluorobenzene 
• 352-34-1 4-fluoro-1-iodobenzene 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 1452406-06-2 1,1,1-trifluoro-6-(4-fluorophenyl)hexan-2-one 
• 1452406-14-2 1,1,1,2,2-pentafluoro-7-(4-fluorophenyl)heptan-3-one 
• 24484-21-7 3-fluoro-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one 
• 1260675-05-5 6-(4-fluorophenyl)tetrahydro-2H-pyran-2-one 
• 1439366-64-9 5-(4-fluorophenyl)-pentyl N-[(2S,3R)-2-methyl-4-oxo-oxetan-3-yl]-carbamate 
• 1439367-35-7 5-(4-fluorophenyl)-pentyl-2-pyridyl-carbonate 
• 1439367-36-8 5-(4-fluorophenyl)pentyl 2-oxopyridine-1-carboxylate 
• 1262615-49-5 5,7-dibenzyloxy-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-3-β-D-[2'',6''-di-O-(4-fluorophenylpentanoyl)-3'',4''-O-isopropylidene]galactosyl-4H-chromen-4-one 
• 204589-96-8 (3R,4S)-4-(4-Benzyloxy-phenyl)-1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-azetidin-2-one 
• 204589-58-2 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)propyl]-(4S)-(4-hydroxyphenyl)-2-azetidinone 

Relevant articles and documents

Cooperative iodine and photoredox catalysis for direct oxidative lactonization of carboxylic acids

A new method for the formation of γ- and δ-lactones from carboxylic acids through direct conversion of benzylic C-H to C-O bonds is described. The reaction is conveniently induced by visible light and relies on a mild cooperative catalysis by the combination of molecular iodine and an organic dye.

Cp2TiCl2-Catalyzed Regioselective Hydrocarboxylation of Alkenes with CO2

Cp2TiCl2-catalyzed regioselective hydrocarboxylation of alkenes with CO2 to give carboxylic acids in high yields has been developed in the presence of iPrMgCl. The reaction proceeds with a wide range of alkenes under mild conditions. Styrene and its derivatives can transform to α-aryl carboxylic acids, and aliphatic alkenes can transform to form alkanoic acids.

First synthesis of N-(4-fluorophenyl)-5-(4-fluorophenyl)-2(4- hydroxybenzyl)pentanamide, a new potential cholesterol absorption inhibitor

The first synthesis of N-(4-fluorophenyl)-5-(4-fluorophenyl)-2-(4- hydroxybenzyl)pentanamide and a new synthesis of 1-(4-fluorophenyl)-3-[(4- fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone starting from 4- fluorobenzaldehyde are described. This new amide could represent a potential new cholesterol absorption inhibitor.