Walrycin B

Base Information

Chemical Name:Walrycin B
CAS No.:878419-78-4
Molecular Formula:C₁₄H₁₀F₃N₅O₂
Molecular Weight:337.261
Hs Code.:
Mol file:878419-78-4.mol

Synonyms:Walrycin B;1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione;1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione Walrycin B;Walrycin B 1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione;Walrycin B, >=98%

Suppliers and Price of Walrycin B

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Walrycin-B >98%
250 mg
$ 600.00

DC Chemicals
Walrycin-B >98%
100 mg
$ 300.00

Crysdot
WalrycinB 98+%
10mg
$ 235.00

Crysdot
WalrycinB 98+%
5mg
$ 158.00

Crysdot
WalrycinB 98+%
50mg
$ 697.00

ChemScene
WalrycinB 96.01%
100mg
$ 650.00

ChemScene
WalrycinB 96.01%
10mg
$ 150.00

ChemScene
WalrycinB 96.01%
5mg
$ 100.00

ChemScene
WalrycinB 96.01%
50mg
$ 450.00

Cayman Chemical
Walrycin B ≥98%
25mg
$ 236.00

Total 22 raw suppliers

Chemical Property of Walrycin B

Chemical Property:

Boiling Point:383.1±52.0 °C(Predicted)
PKA:-2.97±0.20(Predicted)
PSA：82.67000
Density:1.56±0.1 g/cm3(Predicted)
LogP:1.10800
Storage Temp.:Sealed in dry,Store in freezer, under -20°C
Solubility.:≥33.7 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

Purity/Quality:

99%, ^*data from raw suppliers

Walrycin-B >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Walrycin B

There total 3 articles about Walrycin B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

: 1448806-21-0
3-methyl-6-[methyl-[(E)-[4-(trifluoromethyl)phenyl]methyleneamino]amino]-1H-pyrimidine-2,4-dione

: 878419-78-4
1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione

Guidance literature:: 3-methyl-6-[methyl-[(E)-[4-(trifluoromethyl)phenyl]methyleneamino]amino]-1H-pyrimidine-2,4-dione; With acetic acid; sodium nitrite; In water; at 20 ℃; for 18h;

With diothiothreitol; In ethanol; water; at 50 ℃; for 1h;
DOI:10.1021/jm400568p

Reference yield:

: 4318-56-3
3-methyl-6-chlorouracil

: 878419-78-4
1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethanol / 0.17 h / 100 °C / Microwave irradiation

2.1: ethanol / 0.17 h / 50 °C / Microwave irradiation

3.1: acetic acid; sodium nitrite / water / 18 h / 20 °C

3.2: 1 h / 50 °C

With acetic acid; sodium nitrite; In ethanol; water;
DOI:10.1021/jm400568p

Reference yield:

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 42747-84-2
3-methyl-6-(1-methylhydrazinyl)pyrimidine-2,4(1H,3H)-dione

: 878419-78-4
1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol / 0.17 h / 50 °C / Microwave irradiation

2.1: acetic acid; sodium nitrite / water / 18 h / 20 °C

2.2: 1 h / 50 °C

With acetic acid; sodium nitrite; In ethanol; water;
DOI:10.1021/jm400568p