Methyl 3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate

Base Information

Chemical Name:Methyl 3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate
CAS No.:1414377-89-1
Molecular Formula:C11H12O3S
Molecular Weight:224.28
Hs Code.:2934999090
Mol file:1414377-89-1.mol

Synonyms:Methyl 3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate;3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester

Suppliers and Price of Methyl 3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Methyl 3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate

Chemical Property:

Boiling Point:390.8±42.0 °C(Predicted)
PSA：71.61000
Density:1.264±0.06 g/cm3(Predicted)
LogP:2.22600

Purity/Quality:: ≥95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl 3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate

There total 6 articles about Methyl 3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

: 1414642-78-6
methyl 3-(1-hydroxyethyl)-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylate

: 1414377-89-1
3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester

Guidance literature:: With manganese(IV) oxide; In dichloromethane; for 2h; Reflux;

Reference yield: 4.5%

: 3008-40-0
cyclopentane-1,2-dione

: 61363-62-0
methyl [(2-oxopropyl)sulfanyl]acetate

: 1414377-89-1
3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

Reference yield:

: 120-92-3
cyclopentanone

: 1414377-89-1
3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: toluene-4-sulfonic acid / toluene / 4 h / Reflux

2.1: triethylamine / toluene / Reflux

3.1: water; acetic acid / tetrahydrofuran / 48 h / 20 °C

4.1: tetrachloromethane; tributylphosphine / 60 °C

4.2: -10 - 0 °C

5.1: manganese(IV) oxide / dichloromethane / 2 h / Reflux

With tetrachloromethane; manganese(IV) oxide; tributylphosphine; water; toluene-4-sulfonic acid; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane; toluene;