(1S,2S,5R)-Neomenthyl amine

Base Information

Chemical Name:(1S,2S,5R)-Neomenthyl amine
CAS No.:117947-19-0
Molecular Formula:C10H21N
Molecular Weight:191.744
Hs Code.:
DSSTox Substance ID:DTXSID50503899
Nikkaji Number:J259.466H
Wikidata:Q82358003
Mol file:117947-19-0.mol

Synonyms:(1S,2S,5R)-Neomenthyl amine;117947-19-0;(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-amine;(1S, 2S, 5R)-NEOMENTHYL AMINE;SCHEMBL3256236;DTXSID50503899;AKOS006344310;CS-0441967;(1S,2S,5R)-2-ISOPROPYL-5-METHYLCYCLOHEXAN-1-AMINE;(1S,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexan-1-amine

Suppliers and Price of (1S,2S,5R)-Neomenthyl amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
(1S,2S,5R)-Neomenthylamine 98%
5g
$ 6998.00

J&W Pharmlab
(1S,2S,5R)-Neomenthylamine 98%
1g
$ 1880.00

American Custom Chemicals Corporation
(1S,2S,5R)-NEOMENTHYL AMINE 95.00%
1G
$ 745.85

Total 10 raw suppliers

Chemical Property of (1S,2S,5R)-Neomenthyl amine

Chemical Property:

PSA：26.02000
LogP:3.10620
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:155.167399674
Heavy Atom Count:11
Complexity:120

Purity/Quality:

97% ^*data from raw suppliers

(1S,2S,5R)-Neomenthylamine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC(C(C1)N)C(C)C
Isomeric SMILES:C[C@@H]1CC[C@H]([C@H](C1)N)C(C)C

Technology Process of (1S,2S,5R)-Neomenthyl amine

There total 4 articles about (1S,2S,5R)-Neomenthyl amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7231-40-5,787534-09-2
(+)-(1R,3S,4S)-neomenthylamine

: 117947-19-0
(+)-(1S,2S,5R)-5-methyl-2-(1-methylethyl) cyclohexaneammonium chloride

Guidance literature:: With hydrogenchloride; In diethyl ether; at 0 ℃;
DOI:10.1002/anie.201101330

Reference yield:

: 10458-14-7,14073-97-3,17627-49-5,7786-64-3
(2R,5S)-menthone

: 117947-19-0
(+)-(1S,2S,5R)-5-methyl-2-(1-methylethyl) cyclohexaneammonium chloride

Guidance literature:: Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride; sodium carbonate / ethanol; water / 120 h / 25 °C

2: sulfuric acid; N,N,N,N',N',N'-hexamethyl-butane-1,4-diammonium dimethylsulfate / methanol; water / 50 °C / Electrochemical reduction

3: hydrogenchloride / diethyl ether / 0 °C

With hydrogenchloride; sulfuric acid; hydroxylamine hydrochloride; sodium carbonate; N,N,N,N',N',N'-hexamethyl-butane-1,4-diammonium dimethylsulfate; In methanol; diethyl ether; ethanol; water;
DOI:10.1002/anie.201101330

Reference yield:

: 65620-72-6,165874-36-2
(1R,5S)-menthone oxime

: 117947-19-0
(+)-(1S,2S,5R)-5-methyl-2-(1-methylethyl) cyclohexaneammonium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; N,N,N,N',N',N'-hexamethyl-butane-1,4-diammonium dimethylsulfate / methanol; water / 50 °C / Electrochemical reduction

2: hydrogenchloride / diethyl ether / 0 °C

With hydrogenchloride; sulfuric acid; N,N,N,N',N',N'-hexamethyl-butane-1,4-diammonium dimethylsulfate; In methanol; diethyl ether; water;
DOI:10.1002/anie.201101330