2-chloro-4-methoxyphenylacetic acid ethyl ester

Base Information

• Chemical Name: 2-chloro-4-methoxyphenylacetic acid ethyl ester
• CAS No.: 1093758-97-4
• Molecular Formula: C11H13ClO3
• Molecular Weight: 228.675
• Mol file: 1093758-97-4.mol

Synonyms:2-chloro-4-methoxyphenylacetic acid ethyl ester;2-chloro-4-methoxyphenylacetic acid ethylester;ethyl 2-(2-chloro-4-methoxyphenyl)acetate

Chemical Property of 2-chloro-4-methoxyphenylacetic acid ethyl ester

Chemical Property:

• PSA: 35.53000
• LogP: 2.45420

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-chloro-4-methoxyphenylacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-chloro-4-methoxyphenylacetic acid ethyl ester

There total 3 articles about 2-chloro-4-methoxyphenylacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

2-(2-chloro-4-methoxyphenyl)acetic acid (91367-09-8) + ethanol (64-17-5) → (2-chloro-4-methoxy-phenyl)-acetic acid ethyl ester (1093758-97-4)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;

Reference yield: 64.0%

2-(2-chloro-4-methoxyphenyl)acetic acid (91367-09-8) → (2-chloro-4-methoxy-phenyl)-acetic acid ethyl ester (1093758-97-4)

Guidance literature:

With dmap; 1,2-dichloro-ethane; triethylamine; In ethanol; dichloromethane;

Reference yield:

→ (2-chloro-4-methoxy-phenyl)-acetic acid ethyl ester (1093758-97-4)

Guidance literature:

upstream raw materials:

2-(2-chloro-4-methoxyphenyl)acetic acid

ethanol

Downstream raw materials:

2-(2-chloro-4-methoxy-phenyl)-3-(5-methyl-pyrazin-2-yl)-3-oxo-propionic acid ethyl ester