5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-

Base Information

Chemical Name:5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-
CAS No.:951698-15-0
Molecular Formula:C15H18N2O2
Molecular Weight:258.32
Hs Code.:

Synonyms:5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-;5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-3-(phenylmethoxy)-, (.alpha.S)-;[1-(3-Benzyloxy-isoxazol-5-yl)-ally l]-dimethyl-amine;(S)-1-(3-(benzyloxy)isoxazol-5-yl)-N,N-dimethylprop-2-en-1-amine

Suppliers and Price of 5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-

Chemical Property:

Boiling Point:367.3±42.0 °C(Predicted)
PKA:6.48±0.50(Predicted)
PSA：38.50000
Density:1.096±0.06 g/cm3(Predicted)
LogP:3.04230

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl-

There total 10 articles about 5-Isoxazolemethanamine, .alpha.-ethenyl-N,N-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 951698-14-9
C₁₃H₁₃NO₃

: 124-40-3
dimethyl amine

: 951698-15-0
C₁₅H₁₈N₂O₂

Guidance literature:: C₁₃H₁₃NO₃; With methanesulfonyl chloride; triethylamine; In dichloromethane; at -12 - -10 ℃; for 0.5 - 40h;

dimethyl amine; In tetrahydrofuran; dichloromethane; at -40 - 15 ℃; for 4.5 - 7h;

Reference yield:

: 2552-53-6
3-benzyloxy-isoxazole-5-carbaldehyde

: 951698-15-0
C₁₅H₁₈N₂O₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium (1S,2R)-2-(morpholin-4-yl)-1-phenylpropanolate / hexane; toluene / 2.17 h / 0 °C

1.2: hexane; toluene / -75 - -30 °C

2.1: triethylamine / CH₂Cl₂ / 0.5 h / -12 °C

3.1: 76.3 g / tetrahydrofuran; CH₂Cl₂ / 7 h / -30 - 15 °C

With triethylamine; In tetrahydrofuran; hexane; dichloromethane; toluene;
DOI:10.1021/ol071377d

Reference yield:

: 951698-16-1
C₁₃H₁₃NO₃

: 951698-15-0
C₁₅H₁₈N₂O₂

Guidance literature:: Multi-step reaction with 4 steps

1: Amano Lipase AK / hexane / 52.5 h / 23 °C

2: 99 percent / K₂CO₃ / methanol / 0.28 h / 23 °C

3: triethylamine / CH₂Cl₂ / 0.5 h / -12 °C

4: 76.3 g / tetrahydrofuran; CH₂Cl₂ / 7 h / -30 - 15 °C

With Amano Lipase AK; potassium carbonate; triethylamine; In tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1021/ol071377d