3-[2-(Boc-amino)acetamido]benzeneboronic acid pinacol ester, 97%

Base Information

• Chemical Name: 3-[2-(Boc-amino)acetamido]benzeneboronic acid pinacol ester, 97%
• CAS No.: 1257651-17-4
• Molecular Formula: C₁₉H₂₉BN₂O₅
• Molecular Weight: 376.261
• Hs Code.: 2934999090
• Mol file: 1257651-17-4.mol

Synonyms:3-[2-(Boc-amino)acetamido]benzeneboronic acid pinacol ester, 97%;{[3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylcarbamoyl]-methyl}-carbamic acid tert-bu;tert-Butyl(2-oxo-2-{[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]amino}ethyl)carbamate

Chemical Property of 3-[2-(Boc-amino)acetamido]benzeneboronic acid pinacol ester, 97%

Chemical Property:

• Melting Point: 155-160 °C
• PSA: 92.87000
• LogP: 3.30290

Purity/Quality:

97% ^*data from raw suppliers

3-[2-(Boc-amino)acetamido]benzeneboronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-[2-(Boc-amino)acetamido]benzeneboronic acid pinacol ester, 97%

There total 1 articles about 3-[2-(Boc-amino)acetamido]benzeneboronic acid pinacol ester, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

BOC-glycine (4530-20-5) + 3-aminophenylboronic acid pinacolate (210907-84-9) → C19H29BN2O5 (1257651-17-4)

Guidance literature:

With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; at 40 ℃; for 1h;

DOI:10.1039/c3cc45275a

Reference yield:

C19H29BN2O5 (1257651-17-4) → C9H13BN4O3*ClH

Guidance literature:

Multi-step reaction with 4 steps

1: dichloromethane / 4 h / 20 °C

2: water / acetone / 17 h / 20 °C

3: N-ethyl-N,N-diisopropylamine / acetonitrile; water / 2 h / 20 °C

4: hydrogenchloride / 1,4-dioxane / 4 h / 20 °C

With hydrogenchloride; water; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane; water; acetone; acetonitrile;

DOI:10.1039/c3cc45275a

Reference yield:

C19H29BN2O5 (1257651-17-4) → (x)C2HF3O2*C8H11BN2O3

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 4 h / 20 °C

2: water / acetone / 17 h / 20 °C

With water; In dichloromethane; acetone;

DOI:10.1039/c3cc45275a

upstream raw materials:

BOC-glycine

3-aminophenylboronic acid pinacolate