1-EthynylcyclopropanaMine hydrochloride

Base Information

• Chemical Name: 1-EthynylcyclopropanaMine hydrochloride
• CAS No.: 1268810-17-8
• Molecular Formula: C5H8ClN
• Molecular Weight: 117.578
• Mol file: 1268810-17-8.mol

Synonyms:1-EthynylcyclopropanaMine hydrochloride;1-Ethynylcyclopropanamine hydrochloride (1:1);1-Ethynyl-cyclopropylamine hydrochloride

Chemical Property of 1-EthynylcyclopropanaMine hydrochloride

Chemical Property:

• Melting Point: 185-186℃ (decomposition)
• PSA: 26.02000
• LogP: 1.61320
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1-ethynylcyclopropan-1-aminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-EthynylcyclopropanaMine hydrochloride

There total 7 articles about 1-EthynylcyclopropanaMine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

tert-butyl N-(1-ethynylcyclopropyl)carbamate (1268810-09-8) → 1-ethynylcyclopropan-1-amine hydrochloric acid (1268810-17-8)

Guidance literature:

With hydrogenchloride; In diethyl ether; water; at 0 - 20 ℃; for 6h; Darkness;

DOI:10.1055/s-0030-1258964

Reference yield: 87.0%

C10H15NO → 1-ethynylcyclopropan-1-amine hydrochloric acid (1268810-17-8)

Guidance literature:

C₁₀H₁₅NO; With trifluoroacetic acid; In dichloromethane; at 20 ℃;

With hydrogenchloride; tert-butyl methyl ether; In water; at 20 ℃; for 1h;

Reference yield:

tert-butyl N-[1-(2-trimethylsilylethynyl)cyclopropyl]carbamate (1268810-08-7) → 1-ethynylcyclopropan-1-amine hydrochloric acid (1268810-17-8)

Guidance literature:

tert-butyl N-[1-(2-trimethylsilylethynyl)cyclopropyl]carbamate; With potassium fluoride; In water; N,N-dimethyl-formamide; for 16h;

With hydrogenchloride; In 1,4-dioxane; for 16h;

upstream raw materials:

tert-butyl N-(1-ethynylcyclopropyl)carbamate

tert-butyl N-[1-(2-trimethylsilylethynyl)cyclopropyl]carbamate