tert-Butyl [(2S)-1-phenylpropan-2-yl]carbamate

Base Information

Chemical Name:tert-Butyl [(2S)-1-phenylpropan-2-yl]carbamate
CAS No.:293305-71-2
Molecular Formula:C14H21NO2
Molecular Weight:235.326
Hs Code.:
DSSTox Substance ID:DTXSID70573771
Nikkaji Number:J1.413.144B
Wikidata:Q82462592
Mol file:293305-71-2.mol

Synonyms:N-Boc (S)-Amphetamine;293305-71-2;tert-Butyl [(2S)-1-phenylpropan-2-yl]carbamate;TERT-BUTYL N-[(2S)-1-PHENYLPROPAN-2-YL]CARBAMATE;SCHEMBL12203694;DTXSID70573771;AKOS027446993;(s)-t-butyl (1-methyl-2-phenylethyl)-carbamate

Suppliers and Price of tert-Butyl [(2S)-1-phenylpropan-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
N-Boc (S)-amphetamine
10 mg
$ 396.50

Biosynth Carbosynth
N-Boc (S)-amphetamine
5 mg
$ 218.10

Biosynth Carbosynth
N-Boc (S)-amphetamine
2 mg
$ 120.00

Biosynth Carbosynth
N-Boc (S)-amphetamine
50 mg
$ 1310.50

Biosynth Carbosynth
N-Boc (S)-amphetamine
25 mg
$ 721.00

AK Scientific
Tert-Butyl[(2S)-1-phenylpropan-2-yl]carbamate
10mg
$ 585.00

Total 2 raw suppliers

Chemical Property of tert-Butyl [(2S)-1-phenylpropan-2-yl]carbamate

Chemical Property:

PSA：38.33000
LogP:3.53320
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:235.157228913
Heavy Atom Count:17
Complexity:239

Purity/Quality:

97% ^*data from raw suppliers

N-Boc (S)-amphetamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC=CC=C1)NC(=O)OC(C)(C)C
Isomeric SMILES:C[C@@H](CC1=CC=CC=C1)NC(=O)OC(C)(C)C
Uses Protected (S)-Amphetamine.

Technology Process of tert-Butyl [(2S)-1-phenylpropan-2-yl]carbamate

There total 8 articles about tert-Butyl [(2S)-1-phenylpropan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 293305-69-8
(R)-2-(N-t-butoxycarbonylamino)-3-phenyl-1-iodopropane

: 293305-71-2
tert-butyl (1S)-1-methyl-2-phenylethyl carbamate

Guidance literature:: With sodium tri-sec-butylborohydride; In tetrahydrofuran; at 5 ℃; for 1.5h;
DOI:10.1021/jo000242h

Reference yield: 78.0%

: (R)-N-Boc-1-iodo-3-phenyl-2-propylamine

: 293305-71-2
tert-butyl (1S)-1-methyl-2-phenylethyl carbamate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; triethylamine; for 5h; under 760.051 Torr;

Reference yield:

: C₂₁H₂₇N₃O₄S

: 167421-83-2
tert-butyl N-[(1R)-1-methyl-2-phenylethyl]carbamate

: 293305-71-2
tert-butyl (1S)-1-methyl-2-phenylethyl carbamate

Guidance literature:: With zinc(II) fluoride; sodium cyanoborohydride; In toluene; at 80 ℃; for 24h; Overall yield = 15.4 mg;
DOI:10.1021/jacs.1c07726