1-BroMo-4-chloro-2-Methyl-5-nitrobenzene

Base Information

• Chemical Name: 1-BroMo-4-chloro-2-Methyl-5-nitrobenzene
• CAS No.: 10289-13-1
• Molecular Formula: C7H5BrClNO2
• Molecular Weight: 250.479
• Hs Code.: 2904990090
• Mol file: 10289-13-1.mol

Synonyms:1-BroMo-4-chloro-2-Methyl-5-nitrobenzene;2-BroMo-5-chloro-4-nitrotoluene

Chemical Property of 1-BroMo-4-chloro-2-Methyl-5-nitrobenzene

Chemical Property:

• Boiling Point: 313.4±37.0 °C(Predicted)
• PSA: 45.82000
• Density: 1.719±0.06 g/cm3(Predicted)
• LogP: 3.84230
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-5-chloro-4-nitrotoluene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BroMo-4-chloro-2-Methyl-5-nitrobenzene

There total 3 articles about 1-BroMo-4-chloro-2-Methyl-5-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-5-methyl-2-nitrophenylamine (827-32-7) → 1-bromo-4-chloro-2-methyl-5-nitrobenzene (10289-13-1)

Guidance literature:

Multistep reaction; (i) NaNO₂, H₂SO₄, AcOH, (ii) aq. HCl, CuCl;

DOI:10.1021/jm00322a011

Reference yield:

4-bromo-3-methylacetanilide (90914-81-1) → 1-bromo-4-chloro-2-methyl-5-nitrobenzene (10289-13-1)

Guidance literature:

Multi-step reaction with 3 steps

1: (nitration)

2: (hydrolysis)

3: (i) NaNO₂, H₂SO₄, AcOH, (ii) aq. HCl, CuCl

DOI:10.1021/jm00322a011

Reference yield:

N-(4-bromo-5-methyl-2-nitrophenyl)acetamide (716-65-4) → 1-bromo-4-chloro-2-methyl-5-nitrobenzene (10289-13-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (hydrolysis)

2: (i) NaNO₂, H₂SO₄, AcOH, (ii) aq. HCl, CuCl

DOI:10.1021/jm00322a011

upstream raw materials:

4-bromo-5-methyl-2-nitrophenylamine

4-bromo-3-methylacetanilide

N-(4-bromo-5-methyl-2-nitrophenyl)acetamide

Downstream raw materials:

4-Bromo-5-methyl-2-nitro-N-D-ribitylaniline

5-bromo-2-chloro-4-methyl-phenylamine

1-bromo-4-chloro-5-fluoro-2-methyl-benzene

1-bromo-2-bromomethyl-4-chloro-5-fluoro-benzene