4,4,5,5-TETRAMETHYL-2-(2-PHENYL-1-CYCLOHEXEN-1-YL)-1,3,2-DIOXABOROLANE

Base Information

Chemical Name:4,4,5,5-TETRAMETHYL-2-(2-PHENYL-1-CYCLOHEXEN-1-YL)-1,3,2-DIOXABOROLANE
CAS No.:462636-88-0
Molecular Formula:C₁₈H₂₅BO₂
Molecular Weight:284.206
Hs Code.:
Mol file:462636-88-0.mol

Synonyms:4,4,5,5-TETRAMETHYL-2-(2-PHENYL-1-CYCLOHEXEN-1-YL)-1,3,2-DIOXABOROLANE;4,4,5,5-tetramethyl-2-(2-phenylcyclohex-1-enyl)-1,3,2-dioxaborolane;4,4,5,5-tetramethyl-2-(2-phenyl-1-cyclohexen-1-yl)-1,3,2-diox

Suppliers and Price of 4,4,5,5-TETRAMETHYL-2-(2-PHENYL-1-CYCLOHEXEN-1-YL)-1,3,2-DIOXABOROLANE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,4,5,5-Tetramethyl-2-(2-phenyl-1-cyclohexen-1-yl)-1,3,2-dioxaborolane
2.5g
$ 1320.00

Medical Isotopes, Inc.
4,4,5,5-Tetramethyl-2-(2-phenyl-1-cyclohexen-1-yl)-1,3,2-dioxaborolane
250 mg
$ 650.00

Total 5 raw suppliers

Chemical Property of 4,4,5,5-TETRAMETHYL-2-(2-PHENYL-1-CYCLOHEXEN-1-YL)-1,3,2-DIOXABOROLANE

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

4,4,5,5-Tetramethyl-2-(2-phenyl-1-cyclohexen-1-yl)-1,3,2-dioxaborolane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4,4,5,5-Tetramethyl-2-(2-phenyl-1-cyclohexen-1-yl)-1,3,2-dioxaborolane is a reactant in the stereoselective preparation of cyclic boronate derivatives via palladium-catalyzed hydrogenation of alkenylboronates.

Technology Process of 4,4,5,5-TETRAMETHYL-2-(2-PHENYL-1-CYCLOHEXEN-1-YL)-1,3,2-DIOXABOROLANE

There total 5 articles about 4,4,5,5-TETRAMETHYL-2-(2-PHENYL-1-CYCLOHEXEN-1-YL)-1,3,2-DIOXABOROLANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 73183-34-3
bis(pinacol)diborane

: 137058-15-2
3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl trifluoromethanesulfonate

: 462636-88-0
4,4,5,5-tetramethyl-2-(3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)-1,3,2-dioxaborolane

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triphenylphosphine; In 1,4-dioxane; at 80 ℃; for 72h;
DOI:10.1002/anie.201201704

Reference yield:

: 1444-65-1
(RS)-2-phenylcyclohexanone

: 462636-88-0
4,4,5,5-tetramethyl-2-(3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)-1,3,2-dioxaborolane

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triphenylphosphine / 1,4-dioxane / 72 h / 80 °C

With bis-triphenylphosphine-palladium(II) chloride; sodium hydride; potassium carbonate; triphenylphosphine; In 1,4-dioxane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/anie.201201704

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 462636-88-0
4,4,5,5-tetramethyl-2-(3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)-1,3,2-dioxaborolane

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrahydrofuran / 2.67 h / 0 - 20 °C / Inert atmosphere

1.2: 0 °C

1.3: 16 h / 125 °C

2.1: dimethylsulfide; dimethylsulfide borane complex / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2.2: 0 °C

2.3: 20 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C / Inert atmosphere

3.2: Inert atmosphere

4.1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triphenylphosphine / 1,4-dioxane / 72 h / 80 °C

With bis-triphenylphosphine-palladium(II) chloride; dimethylsulfide; dimethylsulfide borane complex; sodium hydride; potassium carbonate; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/anie.201201704