2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID

Base Information

• Chemical Name: 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID
• CAS No.: 174417-54-0
• Molecular Formula: C9H9BrO3
• Molecular Weight: 245.073
• Hs Code.: 2918990090
• Mol file: 174417-54-0.mol

Synonyms:2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID

Chemical Property of 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 353.194°C at 760 mmHg
• Flash Point: 167.406°C
• PSA: 46.53000
• Density: 1.547g/cm³
• LogP: 2.46430
• Storage Temp.: 2-8°C

Purity/Quality:

99%min ^*data from raw suppliers

2-Bromo-5-methoxy-3-methylbenzoic acid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID

There total 6 articles about 2-BROMO-5-METHOXY-3-METHYLBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(2-bromo-5-methoxy-3-methylphenyl)methanol (110451-90-6) → 2-bromo-5-methoxy-3-methylbenzoic acid (174417-54-0)

Guidance literature:

With potassium permanganate; In water; acetone; for 0.5h;

DOI:10.1021/jo972143i

Reference yield:

ammonium hydroxide (1336-21-6) + (2-bromo-5-methoxy-3-methylphenyl)methanol (110451-90-6) → 2-bromo-5-methoxy-3-methylbenzoic acid (174417-54-0)

Guidance literature:

With potassium permanganate; sodium hydrogen sulfate; In acetone;

Reference yield:

2-bromo-5-methoxy-1,3-dimethyl-benzene (6267-34-1) → 2-bromo-5-methoxy-3-methylbenzoic acid (174417-54-0)

Guidance literature:

With jones reagent; calcium carbonate; Yield given. Multistep reaction; 1.) H₂O, dioxane, 5 h; 2.) MeCOMe, 0 degC, 1h;

upstream raw materials:

2-bromo-5-methoxy-1,3-dimethyl-benzene

(2-bromo-5-methoxy-3-methylphenyl)methanol

3,5-dimethylmethoxybenzene

2-bromo-1-(bromomethyl)-5-methoxy-3-methylbenzene

Downstream raw materials:

methyl 2-bromo-5-methoxy-3-methylbenzoate

(S)-2-(2-Bromo-5-methoxy-3-methyl-phenyl)-4-isopropyl-4,5-dihydro-oxazole

Refernces

• 1、 -. "Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions". . . Retrieved 2008/06/13.
• 2、 Solladie, Guy,Hugele, Philippe,Bartsch, Richard. "A New Family of Enantiomerically Pure Smectic C* Liquid Crystals with a Bridged Chiral Biphenyl Core". . p. 3895 - 3898. Retrieved 2007/10/03.