2-Bromo-5-methoxy-1,3-dimethylbenzene

Base Information

• Chemical Name: 2-Bromo-5-methoxy-1,3-dimethylbenzene
• CAS No.: 6267-34-1
• Molecular Formula: C9H11BrO
• Molecular Weight: 215.09
• Hs Code.: 2909309090
• European Community (EC) Number: 613-069-2
• NSC Number: 37991
• DSSTox Substance ID: DTXSID00284601
• Nikkaji Number: J606.100A
• Wikidata: Q72454853
• Mol file: 6267-34-1.mol

Synonyms:2-bromo-5-methoxy-1,3-dimethylbenzene;6267-34-1;4-Bromo-3,5-dimethylanisole;benzene, 2-bromo-5-methoxy-1,3-dimethyl-;MFCD00461692;4-bromo-3,5-dimethylphenyl methyl ether;2-bromo-5-methoxy-1,3-dimethyl-benzene;NSC37991;3,5-dimethyl-4-bromoanisole;SCHEMBL701066;DTXSID00284601;AMY14515;BBL102504;NSC 37991;NSC-37991;STL556307;AKOS004907337;CS-W021621;DS-1812;SY104046;FT-0656565;EN300-84346;A833920;AF-962/00514014;J-514707;2-chloro-5-methoxy-1,3-dimethyl-benzene

Chemical Property of 2-Bromo-5-methoxy-1,3-dimethylbenzene

Chemical Property:

• Vapor Pressure: 0.0209mmHg at 25°C
• Melting Point: 24-25 °C
• Refractive Index: 1.532
• Boiling Point: 259.5 °C at 760 mmHg
• Flash Point: 113.3 °C
• PSA: 9.23000
• Density: 1.326 g/cm³
• LogP: 3.07450
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 213.99933
• Heavy Atom Count: 11
• Complexity: 115

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-5-methoxy-1,3-dimethylbenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1Br)C)OC

Technology Process of 2-Bromo-5-methoxy-1,3-dimethylbenzene

There total 13 articles about 2-Bromo-5-methoxy-1,3-dimethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5-dimethylmethoxybenzene (874-63-5) → 2-bromo-5-methoxy-1,3-dimethyl-benzene (6267-34-1)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 20 ℃; for 12h;

Reference yield: 100.0%

4-bromo-3,5-dimethylphenol (7463-51-6) + methyl iodide (74-88-4) → 2-bromo-5-methoxy-1,3-dimethyl-benzene (6267-34-1)

Guidance literature:

With potassium carbonate; In acetone; for 12h; Reflux;

Reference yield: 99.0%

4-bromo-3,5-dimethylphenol (7463-51-6) + dimethyl sulfate (77-78-1) → 2-bromo-5-methoxy-1,3-dimethyl-benzene (6267-34-1)

Guidance literature:

With potassium carbonate; In acetone; at 40 ℃; for 17h;

DOI:10.1016/j.tetlet.2010.08.035

upstream raw materials:

3,5-dimethylmethoxybenzene

4-bromo-3,5-dimethylphenol

dimethyl sulfate

methyl iodide

Downstream raw materials:

2,6-Dimethyl-4-methoxybenzoic acid

1,3-dibromo-6-methoxy-2,4-dimethylbenzene

C₁₇H₁₉ClO₂

Bis(2,6-dimethyl-4-methoxyphenyl)acetylene