N-ethylpyrazine-2-carboxamide

Base Information

Chemical Name:N-ethylpyrazine-2-carboxamide
CAS No.:74416-46-9
Molecular Formula:C₇H₉N₃O
Molecular Weight:151.168
Hs Code.:
DSSTox Substance ID:DTXSID20409036
Wikidata:Q82214694
Mol file:74416-46-9.mol

Synonyms:N-ethylpyrazine-2-carboxamide;74416-46-9;SCHEMBL2215871;DTXSID20409036;AKOS003857670

Suppliers and Price of N-ethylpyrazine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-ETHYL-PYRAZINECARBOXAMIDE 95.00%
5MG
$ 499.47

Total 3 raw suppliers

Chemical Property of N-ethylpyrazine-2-carboxamide

Chemical Property:

PSA：58.37000
LogP:0.80110
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:151.074561919
Heavy Atom Count:11
Complexity:138

Purity/Quality:

99% ^*data from raw suppliers

N-ETHYL-PYRAZINECARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCNC(=O)C1=NC=CN=C1

Technology Process of N-ethylpyrazine-2-carboxamide

There total 4 articles about N-ethylpyrazine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-97-5
2-pyrazylcarboxylic acid

: 75-04-7,85404-22-4
ethylamine

: 74416-46-9
pyrazine-2-carboxylic acid ethylamide

Guidance literature:: With chloroformic acid ethyl ester; triethylamine; In dichloromethane; -5 deg C to room temp.;

Reference yield:

: 98-97-5
2-pyrazylcarboxylic acid

: 74416-46-9
pyrazine-2-carboxylic acid ethylamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / benzene / 2 h / Reflux

2: dichloromethane / 0 - 20 °C

With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; benzene;
DOI:10.1021/jo502865f