5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic acid

Base Information

Chemical Name:5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic acid
CAS No.:1084953-16-1
Molecular Formula:C14H18BFO5
Molecular Weight:310.13
Hs Code.:
Mol file:1084953-16-1.mol

Synonyms:5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic acid;Methyl 5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate

Suppliers and Price of 5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
Methyl5-fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 98%
1g
$ 519.00

Chemcia Scientific
5-Fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoicacidmethylester 95%
2.5 G
$ 995.00

Chemcia Scientific
5-Fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoicacidmethylester 95%
1 G
$ 495.00

Total 12 raw suppliers

Chemical Property of 5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic acid

Chemical Property:

PSA：53.99000
LogP:1.92010

Purity/Quality:

97% ^*data from raw suppliers

Methyl5-fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic acid

There total 3 articles about 5-fluoro-2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 327-51-5
1,4-dibromo-2,5-difluorobenzene

: 1084953-16-1
methyl 5-fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium / diethyl ether / 0.5 h / -78 °C

1.2: 20 °C

2.1: hydrogenchloride; methanol / 2 h / 65 °C

3.1: sodium methylate; methanol / N,N-dimethyl-formamide / 0.67 h / 0 - 20 °C

4.1: potassium acetate; XPhos / palladium diacetate / N,N-dimethyl acetamide / 24 h / 80 °C

With hydrogenchloride; methanol; n-butyllithium; sodium methylate; potassium acetate; XPhos; palladium diacetate; In diethyl ether; N,N-dimethyl acetamide; N,N-dimethyl-formamide;

Reference yield:

: 1193162-21-8
4-bromo-2,5-difluoro-benzoic acid methyl ester

: 1084953-16-1
methyl 5-fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium methylate; methanol / N,N-dimethyl-formamide / 0.67 h / 0 - 20 °C

2: potassium acetate; XPhos / palladium diacetate / N,N-dimethyl acetamide / 24 h / 80 °C

With methanol; sodium methylate; potassium acetate; XPhos; palladium diacetate; In N,N-dimethyl acetamide; N,N-dimethyl-formamide;